Emapalumab, an Anti-Interferon Gamma Monoclonal Antibody in Two Patients with NLRC4-Related Disease and Severe Hemophagocytic Lymphohistiocytosis (HLH)

被引：0

作者：

Bracaglia, Claudia ^{[1
]}

Prencipe, Giusi ^{[1
]}

Insalaco, Antonella ^{[1
]}

Caiello, Ivan ^{[1
]}

Marucci, Giulia ^{[1
]}

Pecoraro, Raffaele ^{[2
]}

Pardeo, Manuela ^{[1
]}

Dolezalova, Pavla ^{[3
,4
,5
]}

Fingerhutova, Sarka ^{[3
,4
,5
]}

Ballabio, Maria ^{[6
]}

de Min, Cristina ^{[6
]}

De Benedetti, Fabrizio ^{[7
]}

机构：

[1] IRCCS Osped Pediat Bambino Gesu, Div Rheumatol, Rome, Italy

[2] Univ Roma La Sapienza, Dept Pediat, Rome, Italy

[3] Gen Univ Hosp Prague, Paediat Rheumatol Unit, Prague, Czech Republic

[4] Charles Univ Prague, Gen Univ Hosp Prague, Fac Med 1, Prague, Czech Republic

[5] 1st Fac Med, Prague, Czech Republic

[6] NovImmune SA, Geneva, Switzerland

[7] IRCCS Osped Pediat Bambino Gesu, Rome, Italy

来源：

ARTHRITIS & RHEUMATOLOGY | 2018年 / 70卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1415

引用

页数：1

共 27 条

[21] EFFICACY AND SAFETY OF EMAPALUMAB, AN ANTI-INTERFERON GAMMA MONOCLONAL ANTIBODY, IN PATIENTS WITH MACROPHAGE ACTIVATION SYNDROME (MAS) IN SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS (SJIA) WHO HAD FAILED HIGH-DOSE GLUCOCORTICOIDS
De Benedetti, F.
Grom, A.
Brogan, P.
Bracaglia, C.
Pardeo, M.
Marucci, G.
Eleftheriou, D.
Papadopoulou, C.
Quartier, P.
Anton, J.
Frederiksen, R.
Asnaghi, V.
de Min, C.
ANNALS OF THE RHEUMATIC DISEASES, 2022, 81 : 128 - 128
[22] EMAPALUMAB (ANTI-INTERFERON-GAMMA MONOCLONAL ANTIBODY) IN PATIENTS WITH MACROPHAGE ACTIVATION SYNDROME (MAS) COMPLICATING SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS (SJIA)
De Benedetti, F.
Brogan, P.
Bracaglia, C.
Pardeo, M.
Marucci, G.
Sacco, E.
Eleftheriou, D.
Papadopoulou, C.
Grom, A.
Quartier, P.
Schneider, R.
Jacqmin, P.
Frederiksen, R.
Ballabio, M.
De Min, C.
ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 : 180 - 180
[23] Emapalumab (Anti-Interferon-Gamma Monoclonal Antibody) in Patients with Macrophage Activation Syndrome (MAS) Complicating Systemic Juvenile Idiopathic Arthritis (sJIA)
De Benedetti, Fabrizio
Brogan, Paul
Bracaglia, Claudia
Pardeo, Manuela
Marucci, Giulia
Sacco, Emanuela
Eleftheriou, Despina
Papadopoulou, Charalampia
Grom, Alexei
Quartier, Pierre
Schneider, Rayfel
Jacqmin, Philippe
Frederiksen, Rikke
Ballabio, Maria
de Min, Cristina
ARTHRITIS & RHEUMATOLOGY, 2020, 72 : 14 - 16
[24] Fontolizumab, a humanised anti-interferon γ antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease
Hommes, D. W.
Mikhajlova, T. L.
Stoinov, S.
Stimac, D.
Vucelic, B.
Lonovics, J.
Zakuciova, M.
D'Haens, G.
Van Assche, G.
Ba, S.
Lee, S.
Pearce, T.
GUT, 2006, 55 (08) : 1131 - 1137
[25] USE OF EMAPALUMAB (ANTI-INTERFERON-GAMMA MONOCLONAL ANTIBODY) FOR ACTIVE DISEASE CONTROL FOLLOWED BY HEMATOPOETIC CELL TRANSPLANTATION IN A PATIENT WITH REFRACTORY SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS WITH ASSOCIATED LUNG DISEASE
Chellapandian, Deepak
Vaughn, Gretchen
Milojevic, Diana
PEDIATRIC BLOOD & CANCER, 2023, 70 : S7 - S8
[26] A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon γ antibody, in patients with moderate to severe Crohn's disease
Reinisch, W.
Hommes, D. W.
Van Assche, G.
Colombel, J. -F.
Gendre, J. -P.
Oldenburg, B.
Teml, A.
Geboes, K.
Ding, H.
Zhang, L.
Tang, M.
Cheng, M.
van Deventer, S. J. H.
Rutgeerts, P.
Pearce, T.
GUT, 2006, 55 (08) : 1138 - 1144
[27] EMERALD STUDY DESIGN: A TWO-COHORT, OPENLABEL, SINGLE-ARM STUDY OF EMAPALUMAB, AN ANTI-INTERFERON-G (IFNG) MONOCLONAL ANTIBODY, IN PATIENTS WITH MACROPHAGE ACTIVATION SYNDROME (MAS) IN RHEUMATIC DISEASES
De Benedetti, F.
Krmar, R.
Kanceva, R.
Grom, A.
ANNALS OF THE RHEUMATIC DISEASES, 2023, 82 : 1969 - 1970

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