Preliminary evaluation of a monolithic detector module for integrated PET/MRI scanner with high spatial resolution

被引：21
|
作者：
Pani, R. [1 ]
Gonzalez, A. J. [2 ]
Bettiol, M. [1 ,3 ]
Fabbri, A. [1 ]
Cinti, M. N. [1 ]
Preziosi, E. [1 ,4 ]
Borrazzo, C. [1 ,3 ]
Conde, P. [2 ]
Pellegrini, R. [1 ]
Di Castro, E. [5 ]
Majewski, S. [6 ]
机构：
[1] Univ Roma La Sapienza, Dept Mol Med, I-00185 Rome, Italy
[2] CSIC, I3M, Valencia 46022, Spain
[3] Univ Roma La Sapienza, Postgrad Sch Med Phys, I-00185 Rome, Italy
[4] Univ Roma La Sapienza, SAIMLAL Dept, Doctorate Sch Biol & Mol Med, Morphofunct Sci Biophys, I-00185 Rome, Italy
[5] Univ Roma La Sapienza, Dept Radiol Sci Oncol & Pathol, I-00185 Rome, Italy
[6] W Virginia Univ, Dept Radiol, Ctr Adv Imaging, Morgantown, WV 26506 USA
来源：
JOURNAL OF INSTRUMENTATION | 2015年 / 10卷
关键词：
Gamma camera; SPECT; PET PET/CT; coronary CT angiography (CTA); Medical-image reconstruction methods and algorithms; computer-aided software; Multi-modality systems;
D O I：
10.1088/1748-0221/10/06/C06006
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
The proposal of Mindview European Project concerns with the development of a very high resolution and high efficiency brain dedicated PET scanner simultaneously working with a Magnetic Resonance scanner, that expects to visualize neurotransmitter pathways and their disruptions in the quest to better diagnose schizophrenia. On behalf of this project, we propose a low cost PET module for the first prototype, based on monolithic crystals, suitable to be integrated with a head Radio Frequency (RF) coil. The aim of the suggested module is to achieve high performances in terms of efficiency, planar spatial resolution (expected about 1 mm) and discrimination of gamma Depth Of Interaction (DOI) in order to reduce the parallax error. Our preliminary results are very promising: a DOI resolution of about 3 mm, a spatial resolution ranging from about 1 to 1.5 mm and a good position linearity.
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页数：10
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