1,1-Bis(dimethylamino)-2,2-difluoroethene, a diverse building block for the preparation of difluoroalkyl molecules. Acylation and condensation reactions

被引：4

作者：

Xu, Yuelian ^{[1
]}

Lopez, Simon E. ^{[1
]}

Dolbier, William R., Jr. ^{[1
]}

机构：

[1] Univ Florida, Dept Chem, POB 117200, Gainesville, FL 32611 USA

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2020年 / 229卷

基金：

美国国家科学基金会;

关键词：

Fluorinated ketene aminal; Acylation reactions; FLUORINE;

D O I：

10.1016/j.jfluchem.2019.109432

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

1,1-Bis(dimethylamino)-2,2-difluoroethene has been shown to be a diverse and highly effective building block for the preparation of a variety of fluorinated compounds. Reported here are preliminary results of its use for acylation reactions with acyl chlorides to form 2,2-difluoroketoacetamides as well as for its direct condensation with various acidic a-hydrogen carbon compounds to form a variety of functionalized difluoromethyl enamines.

引用

页数：5

共 26 条

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[25] Simple and high yield synthesis of ( QQ )10,10'-dimethyl-dotriacontan-1,1'-diol as a building block for branched bola compounds. Preparation of ( QQ )10,10'-dimethyl-dotriaconta-1,1'-diyl-bis$L B@2-( trimethylammonio)ethyl phosphate] and the corresponding unbranched equivalent
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