A Population-Based Cohort Study of HRT Use and Breast Cancer in Korea
被引:7
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作者:
Park, Sat Byul
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机构:
Duke Univ, Med Ctr, Durham, NC USAAjou Univ, Dept Family Practice & Community Hlth, Sch Med, Suwon 443721, South Korea
Park, Sat Byul
[2
]
Shin, Hai Rim
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机构:
Natl Canc Ctr, Natl Canc Control Inst, Goyang, South Korea
Int Agcy Res Canc, F-69372 Lyon, FranceAjou Univ, Dept Family Practice & Community Hlth, Sch Med, Suwon 443721, South Korea
Shin, Hai Rim
[3
,4
]
Lee, Soon Young
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机构:
Ajou Univ, Dept Family Practice & Community Hlth, Sch Med, Suwon 443721, South KoreaAjou Univ, Dept Family Practice & Community Hlth, Sch Med, Suwon 443721, South Korea
Lee, Soon Young
[1
]
机构:
[1] Ajou Univ, Dept Family Practice & Community Hlth, Sch Med, Suwon 443721, South Korea
[2] Duke Univ, Med Ctr, Durham, NC USA
[3] Natl Canc Ctr, Natl Canc Control Inst, Goyang, South Korea
The incidence of breast cancer has recently been ranked first in Korea. This is a population-based cohort study that aims to evaluate the risk of breast cancer from the use of hormone replacement therapy (HRT). A total of 9579 participants were observed between January 1998 and June 2004; 6108 women who took HRT constituted the HRT group, and 3471 women who did not take HRT constituted the non-HRT group. Using the database from the Korea Central Cancer Registry, the authors examined the incidence of breast cancer from HRT. A total of 26 cases of breast cancer developed in the HRT group as compared with the 13 cases in the non-HRT group, during the follow-up period. The relative risk of developing breast cancer in the HRT group was 1.16 times higher than in the non-HRT group, with a population attributable risk of 29.9%. The risk of breast cancer in the HRT group increased when the risk factors were adjusted in the model.
机构:
Natl Canc Ctr, Grad Sch Canc Sci & Policy, Canc Control & Populat Hlth, Goyang Si, South KoreaNatl Canc Ctr, Grad Sch Canc Sci & Policy, Canc Control & Populat Hlth, Goyang Si, South Korea
Tran, T. T. P.
Luu, N. M.
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Natl Canc Ctr, Grad Sch Canc Sci & Policy, Canc Control & Populat Hlth, Goyang Si, South KoreaNatl Canc Ctr, Grad Sch Canc Sci & Policy, Canc Control & Populat Hlth, Goyang Si, South Korea
Luu, N. M.
Bui, T. T.
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机构:
Natl Canc Ctr, Grad Sch Canc Sci & Policy, Canc Control & Populat Hlth, Goyang Si, South KoreaNatl Canc Ctr, Grad Sch Canc Sci & Policy, Canc Control & Populat Hlth, Goyang Si, South Korea
Bui, T. T.
Han, M.
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机构:
Natl Canc Ctr, Div Canc Prevent, Goyang Si, South KoreaNatl Canc Ctr, Grad Sch Canc Sci & Policy, Canc Control & Populat Hlth, Goyang Si, South Korea
Han, M.
Lim, M. K.
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机构:
Inha Univ, Coll Med, Dept Social & Prevent Med, Incheon, South KoreaNatl Canc Ctr, Grad Sch Canc Sci & Policy, Canc Control & Populat Hlth, Goyang Si, South Korea
Lim, M. K.
Oh, J-K.
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机构:
Natl Canc Ctr, Div Canc Prevent, Goyang Si, South KoreaNatl Canc Ctr, Grad Sch Canc Sci & Policy, Canc Control & Populat Hlth, Goyang Si, South Korea
机构:
Kuwait Univ, Fac Med, Dept Community Med & Behav Sci Biostat, Safat 13110, KuwaitKuwait Univ, Fac Med, Dept Community Med & Behav Sci Biostat, Safat 13110, Kuwait
Thalib, Lukman
Hall, Per
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机构:
Karolinska Inst, Dept Med Epidemiol & Biostat, S-17177 Stockholm, SwedenKuwait Univ, Fac Med, Dept Community Med & Behav Sci Biostat, Safat 13110, Kuwait