Immune Regulation of Heme Oxygenase-1 in Allergic Airway Inflammation

被引：7
|
作者：
Xia, Zhenwei [1 ]
Zhong, Wenwei [2 ]
机构：
[1] Shanghai Jiao Tong Univ, Dept Pediat, Ruijin Hosp, Sch Med, 197 Ruijin 2nd Rd, Shanghai 200025, Peoples R China
[2] Shanghai Jiao Tong Univ, Dept Pediat, Xinhua Hosp, Sch Med, 1665 Kongjiang Rd, Shanghai 200090, Peoples R China
来源：
ANTIOXIDANTS | 2022年 / 11卷 / 03期
基金：
中国国家自然科学基金;
关键词：
heme oxygenase-1; asthma; airway inflammation; immunoregulation; DENDRITIC CELL MATURATION; EXHALED CARBON-MONOXIDE; T-CELLS; UP-REGULATION; ANTIGEN PRESENTATION; PROTECTIVE ROLE; MOUSE MODEL; MAST-CELLS; ACTIVATION; EXPRESSION;
D O I：
10.3390/antiox11030465
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Heme oxygenase-1 (HO-1) is not only a rate-limiting enzyme in heme metabolism but is also regarded as a protective protein with an immunoregulation role in asthmatic airway inflammation. HO-1 exerts an anti-inflammation role in different stages of airway inflammation via regulating various immune cells, such as dendritic cells, mast cells, basophils, T cells, and macrophages. In addition, the immunoregulation role of HO-1 may differ according to subcellular locations.
引用
收藏
页数：13
相关论文
共 50 条
  • [31] Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression
    Sebastian, Valentina P.
    Salazar, Geraldyne A.
    Coronado-Arrazola, Irenice
    Schultz, Barbara M.
    Vallejos, Omar P.
    Berkowitz, Loni
    Alvarez-Lobos, Manuel M.
    Riedel, Claudia A.
    Kalergis, Alexis M.
    Bueno, Susan M.
    FRONTIERS IN IMMUNOLOGY, 2018, 9
  • [32] Heme oxygenase-1 system and gastrointestinal inflammation:A short review
    Hsiangfu Kung
    Marie CM Lin
    World Journal of Gastroenterology, 2011, 17 (38) : 4283 - 4288
  • [33] Heme oxygenase-1 system and gastrointestinal inflammation: A short review
    Zhu, Xiao
    Fan, Wen-Guo
    Li, Dong-Pei
    Kung, Hsiangfu
    Lin, Marie C. M.
    WORLD JOURNAL OF GASTROENTEROLOGY, 2011, 17 (38) : 4283 - 4288
  • [34] Protective role of heme oxygenase-1 against inflammation in atherosclerosis
    Durante, William
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2011, 16 : 2372 - 2388
  • [35] Heme Oxygenase-1 Expressed Macrophages Inhibit Intestinal Inflammation
    Naito, Y.
    Higashimura, Y.
    Mizushima, K.
    Katada, K.
    Takagi, T.
    DIGESTIVE DISEASES AND SCIENCES, 2014, 59 (08) : 1660 - 1660
  • [36] Heme Oxygenase-1 Controls Post-Ischemic Inflammation
    Jazwa, A.
    Tomczyk, M.
    Kraszewska, I.
    Szade, K.
    Bukowska-Strakova, K.
    Jozkowicz, A.
    Dulak, J.
    JOURNAL OF VASCULAR RESEARCH, 2017, 54 : 41 - 41
  • [37] Heme oxygenase-1/carbon monoxide as modulators of autophagy and inflammation
    Ryter, Stefan W.
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2019, 678
  • [38] Heme Oxygenase-1 and Iron in Liver Inflammation: A Complex Alliance
    Immenschuh, Stephan
    Baumgart-Vogt, Eveline
    Mueller, Sebastian
    CURRENT DRUG TARGETS, 2010, 11 (12) : 1541 - 1550
  • [39] Targeting of heme oxygenase-1 as a novel immune regulator of neuroblastoma
    Fest, Stefan
    Soldati, Rocio
    Christiansen, Nina M.
    Zenclussen, Maria L.
    Kilz, Jana
    Berger, Elisa
    Starke, Sven
    Lode, Holger N.
    Engel, Christoph
    Zenclussen, Ana C.
    Christiansen, Holger
    INTERNATIONAL JOURNAL OF CANCER, 2016, 138 (08) : 2030 - 2042
  • [40] Heme Oxygenase-1 Deficiency
    Renji, Soumya
    Shah, Nitin
    Madkaikar, Manisha
    INDIAN PEDIATRICS, 2021, 58 (03) : 290 - 291
12345