Synthesis and antifungal activity of ω-(1-aryl-5-methyl-1,2,3-triazole-4-carboxyl)-ω-(1H-1,2,4-triazol-1-yl)acetophenones

被引:0
|
作者
Chu, CH
Sun, XW
Zhang, ZY [1 ]
Li, ZC
Liao, RA
机构
[1] Lanzhou Univ, Dept Chem, Natl Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
关键词
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Several omega-(1-aryl-5-methyl-1,2,3-triazole-4-carboxyl)-omega-(1H-1,2,4-triazol-1-yl)acetophenones 3a-j have been synthesized. The structures of these compounds have been confirmed by elemental analyses and spectral data. The preliminary biological test results show that the representative compounds exhibit mild antifungal activities.
引用
收藏
页码:854 / 856
页数:3
相关论文
共 50 条
  • [31] Synthesis and antimicrobial activity of 5-(1H-1,2,3-triazol-4-yl)-1,2,4-oxadiazole derivatives
    Krolenko, Konstantin Yu.
    Vlasov, Sergiy V.
    Zhuravel, Irina A.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2016, 52 (10) : 823 - 830
  • [33] Design, synthesis and antifungal evaluation of 1-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)-1H-1,2,4-triazol-5(4H)-one
    Jiang, Yongwei
    Cao, Yongbin
    Zhang, Jun
    Zou, Yan
    Chai, Xiaoyun
    Hu, Honggang
    Zhao, Qingjie
    Wu, Qiuye
    Zhang, Dazhi
    Jiang, Yuanying
    Sun, Qingyan
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 46 (07) : 3135 - 3141
  • [34] Studies on the derivatives of ω-aryloxyacetoxy ω-(1H-1,2,4-triazol-1-yl)acetophenone
    Shi, Yan-Nian
    Lu, Yan-Chang
    Fang, Jian-Xin
    Hua, Yan-Ling
    Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities, 1995, 16 (11):
  • [35] 2-[4-(1H-1,2,4-Triazol-1-yl) phenyl]-1Hbenzimidazole
    Cheng, Long-Huai
    Zheng, Zheng
    Han, Zhi-Li
    Wu, Zhi-Chao
    Zhou, Hong-Ping
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O2890 - +
  • [36] REACTION OF α-(1H-1,2,4-TRIAZOL-1-YL)ACETOPHENONE WITH PHENYL ISOTHIOCYANATE
    Zheng Ming LI Zhen Nian HUANG Institute of Elemento-Organic Chemistry
    Chinese Chemical Letters, 1993, (09) : 763 - 766
  • [37] Diaquabis{5-carboxy-2-[(1H-1,2,4-triazol-1-yl)methyl]-1H-imidazole-4-carboxylato}manganese(II)
    Ding, De-Gang
    Tong, Yan
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : M517 - U474
  • [38] 4-tert-Butyl-5-(1H-1,2,4-triazol-1-yl)thiazol-2-amine
    Xie, An-Yun
    Ye, Jiao
    Qin, Zhi
    Hu, Ai-Xi
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O2057 - U4689
  • [39] Synthesis, structure and biological activities of 2-(1H-1,2,3-benzotriazol-1yl)-1-(4-methylphenyl)-2-(1H-1,2,4-triazol-1-yl)-1-ethanone
    Wan Jun
    Li Chun-li
    Li Xue-mei
    Zhang Shu-sheng
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2006, 22 (04) : 465 - 467
  • [40] Syntheses, crystal structures and properties of [(1H-1,2,4-Triazol-1-yl)methyl]ferrocene complexes
    Zhou Xiao-Li
    Li Lin-Ke
    Song Ying-Lin
    Hou Hong-Wei
    Fan Yao-Ting
    Meng Jing-Jing
    ACTA CHIMICA SINICA, 2008, 66 (07) : 775 - 782