Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series

被引：3

作者：

Shangguan, Yanwan ^{[1
]}

Ji, Zhongkang ^{[1
]}

Guo, Wanru ^{[1
]}

Hu, Wenjuan ^{[1
]}

Li, Xiaomeng ^{[1
]}

Xu, Kaijin ^{[1
,2
]}

机构：

[1] Zhejiang Univ, Affiliated Hosp 1, Collaborat Innovat Ctr Diag & Treatment Infect Dis, Natl Med Ctr Infect Dis,Sch Med,State Key Lab Diag, Hangzhou, Peoples R China

[2] Zhejiang Univ, Natl Clin Res Ctr Med, State Key Lab Diag & Treatment Infect Dis, Collaborat Innovat Ctr Diag & Treatment Infect Dis, Hangzhou, Peoples R China

来源：

INFECTION AND DRUG RESISTANCE | 2022年 / 15卷

关键词：

tuberculosis infection; linezolid; treatment; side-effect; black-hairy tongue; microorganism metabolism;

D O I：

10.2147/IDR.S373266

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Linezolid-induced black hairy tongue is a self-limiting benign disease that is rare. Here, we report three patients who developed black hairy tongue after linezolid treatment. The severe dysbiosis of oral bacterial communities was observed in all these patients. Proteobacteria was the most prevalent phylum (over 90%) at the black tongue stage. Furthermore, the dramatic oral bacterial alteration took a long time to reverse after the BHT resolved.

引用

页码：5449 / 5454

页数：6

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