Coronavirus Disease 2019 in a Patient With a Systemic Autoinflammatory Syndrome due to an NLRC4 Inflammasomopathy

被引：3
|
作者：
Duncan-Lowey, Jeffrey K. [1 ,2 ]
Chowdhary, Vaidehi [3 ]
Dunne, Dana W. [1 ]
机构：
[1] Yale Univ, Sch Med, Dept Med, Sect Infect Dis, New Haven, CT 06510 USA
[2] Yale Univ, Sch Med, Yale MD PhD Program, New Haven, CT USA
[3] Yale Univ, Sch Med, Dept Med, Sect Rheumatol, New Haven, CT 06510 USA
来源：
OPEN FORUM INFECTIOUS DISEASES | 2021年 / 8卷 / 08期
基金：
美国国家卫生研究院;
关键词：
COVID-19; SARS-CoV-2; autoinflammatory; inflammasome; NLRC4;
D O I：
10.1093/ofid/ofab362
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The effect of autoinflammatory diseases on severe acute respiratory syndrome coronavirus 2 infection remains unknown. We report a case of coronavirus disease 2019 (COVID-19) in a patient with autoinflammation with infantile enterocolitis with inflammatory flares due to a mutation in the inflammasome component NLRC4. This case highlights the role of immunosuppression in patients with autoinflammation with COVID-19.
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页数：4
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