Eremophilane-type glucosides from the leaves of Ligularia calthifolia Maxim

被引：4

作者：

Ponomarenko, Ludmila P. ^{[1
]}

Ermolaeva, Sophia D. ^{[1
]}

Doudkin, Roman V. ^{[1
,2
,3
]}

Dyshlovoy, Sergey A. ^{[1
,2
,4
]}

Gorovoy, Petr G. ^{[1
]}

机构：

[1] Russian Acad Sci, Far Eastern Branch, GB Elyakov Pacific Inst Bioorgan Chem, Pr 100 Let Vladivostoku 159, Vladivostok 690022, Russia

[2] Far Eastern Fed Univ, 8 Sukhanova St, Vladivostok 690090, Russia

[3] Russian Acad Sci, Bot Garden Inst, Far Eastern Branch, Makovskii Str 142, Vladivostok 690024, Russia

[4] Univ Med Ctr Hamburg Eppendorf, Lab Expt Oncol, Dept Oncol Hematol & Bone Marrow Transplantat, Sect Pneumol,Hubertus Wald Tumorzentrum, Hamburg, Germany

来源：

PHYTOCHEMISTRY LETTERS | 2017年 / 21卷

关键词：

Ligularia calthifolia; Eremophilane-type sesquiterpene glucosides; NMR; PETASITES-JAPONICUS; ALTICOLA WOROSCH; SESQUITERPENOIDS;

D O I：

10.1016/j.phytol.2017.07.013

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three eremophilane-type glucosides (1-3) along with three known congeners alticolosides A, B and D (4-6) have been isolated from the leaves of Ligularia calthifolia Maxim. (Asteraceae). The structures of 1-3 have been elucidated by spectroscopic analysis as well as by chemical transformations. A distinctive feature of the compounds 1-3 is the presence of an acetyl group in the glucose residues. The compounds were non-cytotoxic against human normal prostate cells as well as prostate cancer cells.

引用

页码：264 / 268

页数：5

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