One-pot synthesis of β-amino carbonyl compounds catalyzed silica supported phenylphosphinic acid

被引：1
|
作者：
Liu, Di [1 ]
Zhang, Jingwei [1 ]
Zhang, Chi [1 ]
Kou, Xiaoyan [1 ]
机构：
[1] Shandong Univ Sci & Technol, Coll Chem & Environm Engn, Qingdao 266590, Peoples R China
来源：
GREEN PROCESSING AND SYNTHESIS | 2015年 / 4卷 / 01期
基金：
中国博士后科学基金; 中国国家自然科学基金; 高等学校博士学科点专项科研基金;
关键词：
beta-amino carbonyl compounds; Mannich reaction; silica supported phenylphosphinic acid; synthesis; MANNICH REACTION; 3-COMPONENT SYNTHESIS; FACILE SYNTHESIS; IONIC LIQUIDS; KETONES; SALTS;
D O I：
10.1515/gps-2014-0077
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple and facile synthesis of beta-amino carbonyl compounds was developed by the one-pot condensation of cyclohexanone, aromatic aldehydes and anilines at 25 degrees C in the presence of silica supported phenylphosphinic acid. beta-Amino carbonyl compounds were obtained in moderate to good yields and reasonable diastereoselectivities. This method has the advantages of short reaction time, mild reaction conditions, reusable catalyst, cost efficiency and environment friendly. In addition, acetophenone and aliphatic ketones as reactants were investigated.
引用
收藏
页码：11 / 15
页数：5
相关论文
共 50 条
  • [21] Rare earth perfluorooctanoate [RE(PFO)3] catalyzed one-pot Mannich reaction:: three component synthesis of β-amino carbonyl compounds
    Wang, LM
    Han, JW
    Sheng, J
    Tian, H
    Fan, ZY
    CATALYSIS COMMUNICATIONS, 2005, 6 (03) : 201 - 204
  • [22] An Efficient One-pot Synthesis of β-Amino/β-Acetamido Carbonyl Compounds via ZrCl4-catalyzed Mannich-type Reaction
    Sanjeeva, Reddy Cherkupally
    Purnachandra, Reddy Gurrala
    CHINESE JOURNAL OF CHEMISTRY, 2008, 26 (12) : 2216 - 2222
  • [23] Basic Functionalized Ionic Liquid Catalyzed One-pot Mannich-type Reaction: Three Component Synthesis of β-Amino Carbonyl Compounds
    Kai Gong
    Dong Fang
    Hua-Lan Wang
    Zu-Liang Liu
    Monatshefte für Chemie - Chemical Monthly, 2007, 138 : 1195 - 1198
  • [24] One-pot dehydrogenation of carboxylic acid derivatives to α,β-unsaturated carbonyl compounds
    Matsuo, J
    LETTERS IN ORGANIC CHEMISTRY, 2005, 2 (07) : 576 - 577
  • [25] Solvent-free one-pot synthesis of amidoalkyl naphthols catalyzed by silica sulfuric acid
    Srihari, Galla
    Nagaraju, Manda
    Murthy, Madugula Marthanda
    HELVETICA CHIMICA ACTA, 2007, 90 (08) : 1497 - 1504
  • [26] One Pot Synthesis of Multiaryl-Substituted β-Amino Ketone Compounds Catalyzed by Silica-Supported Rare Earth Terbium Chloride
    Ma, Xuelin
    Zhang, Xiaoyang
    Li, Xuan
    Liu, Yongming
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2013, 33 (03) : 602 - 606
  • [27] Silica chloride catalyzed one-pot synthesis of fully substituted pyrazoles
    Dhanaji V.Jawale
    Umesh R.Pratap
    Jyotirling R.Mali
    Ramrao A.Mane
    ChineseChemicalLetters, 2011, 22 (10) : 1187 - 1190
  • [28] Silica chloride catalyzed one-pot synthesis of fully substituted pyrazoles
    Jawale, Dhanaji V.
    Pratap, Umesh R.
    Mali, Jyotirling R.
    Mane, Ramrao A.
    CHINESE CHEMICAL LETTERS, 2011, 22 (10) : 1187 - 1190
  • [29] One-pot synthesis of β-amino acid derivatives from α-amino acids
    Saavedra, Carlos J.
    Hernandez, Rosendo
    Boto, Alicia
    Alvarez, Eleuterio
    TETRAHEDRON LETTERS, 2006, 47 (49) : 8757 - 8760
  • [30] Three component synthesis of β-amino carbonyl compounds using indium trichloride-catalyzed one-pot Mannich-type reaction in water
    Loh, TP
    Liung, SBKW
    Tan, KL
    Wei, LL
    TETRAHEDRON, 2000, 56 (20) : 3227 - 3237
12345