Characterization and evolution of major histocompatibility complex class II genes in the aye-aye, Daubentonia madagascariensis

被引：6
|
作者：
Go, Y [1 ]
Rakotoarisoa, G
Kawamoto, Y
Shima, T
Koyama, N
Randrianjafy, A
Mora, R
Hirai, H
机构：
[1] Grad Univ Adv Studies, Dept Biosyst Sci, Kanagawa 2400193, Japan
[2] Kyoto Univ, Primate Res Inst, Inuyama, Aichi 484, Japan
[3] Parc Bot & Zool Tsimbazaza, Antananarivo, Madagascar
[4] Kyoto Univ, Ctr African Area Studies, Kyoto, Japan
来源：
PRIMATES | 2005年 / 46卷 / 02期
关键词：
aye-aye; conservation; evolution; madagascar; major histocompatibility complex;
D O I：
10.1007/s10329-004-0101-0
中图分类号：
Q95 [动物学];
学科分类号：
071002 ;
摘要：
Major histocompatibility complex genes (Mhc-DQB and Mltc-DRB) were sequenced in seven aye-ayes (Daubentonia madagascariecsis), which is an endemic and endangered species in Madagascar. An aye-aye from a north-eastern population showed genetic relatedness to individuals of a north-western population and had a somewhat different repertoire from another north-eastern individual. These observations suggest that the extent of genetic variation in Mhc genes is not excessively small in the aye-aye in spite of recent rapid destruction of their habitat by human activities. In light of Mhc gene evolution, trans-species and allelic poly-morphisms can be estimated to have been retained for more than 50 Ma (million years) based on the time scale of lemur evolution.
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页码：135 / 139
页数：5
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