Bioadhesion: a review of concepts and applications

被引：103

作者：

Palacio, Manuel L. B. ^{[1
]}

Bhushan, Bharat ^{[1
]}

机构：

[1] Ohio State Univ, Nanoprobe Lab Bio & Nanotechnol & Biomimet, Columbus, OH 43210 USA

来源：

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES | 2012年 / 370卷 / 1967期

关键词：

bioadhesion; bioadhesives; cell adhesion; mucoadhesion; SILICON-BASED SURFACES; CELL-ADHESION; INTEGRIN BINDING; ADSORPTION THERMODYNAMICS; VARYING FUNCTIONALITY; THEORETICAL-ANALYSIS; PEPTIDE RESIDUES; SAM SURFACES; FIBRONECTIN; PROTEINS;

D O I：

10.1098/rsta.2011.0483

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Bioadhesion refers to the phenomenon where natural and synthetic materials adhere to biological surfaces. An understanding of the fundamental mechanisms that govern bioadhesion is of great interest for various researchers who aim to develop new biomaterials, therapies and technological applications such as biosensors. This review paper will first describe various examples of the manifestation of bioadhesion along with the underlying mechanisms. This will be followed by a discussion of some of the methods for the optimization of bioadhesion. Finally, nanoscale and macroscale characterization techniques for the efficacy of bioadhesion and the analysis of failure surfaces are described.

引用

页码：2321 / 2347

页数：27

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