Glucocorticoids in pediatric inflammatory bowel disease

被引：18
|
作者：
Sidoroff, Marianne [1 ]
Kolho, Kaija-Leena
机构：
[1] Univ Helsinki, Childrens Hosp, Helsinki 00029, Finland
来源：
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | 2012年 / 47卷 / 07期
关键词：
children; Crohn's disease; steroid; ulcerative colitis; BONE-MINERAL DENSITY; ULCERATIVE-COLITIS; CROHNS-DISEASE; CORTICOSTEROID-THERAPY; MONONUCLEAR-CELLS; ORAL PREDNISOLONE; BCLI POLYMORPHISM; STEROID TREATMENT; NATURAL-HISTORY; MESSENGER-RNA;
D O I：
10.3109/00365521.2012.679681
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Children with moderate to severe inflammatory bowel disease (IBD) are treated with systemic glucocorticoids (GCs). The majority of the patients respond to the given treatment; however, steroid resistance and dependency are significant clinical problems. Also therapy-related side effects limit the use of GCs in the control of active inflammation. This review summarizes recent knowledge of GC treatment in pediatric patients with IBD.
引用
收藏
页码：745 / 750
页数：6
相关论文
共 50 条
  • [21] Challenges in pediatric inflammatory bowel disease
    Bousvaros, Athos
    Sylvester, Francisco
    Kugathasan, Subra
    Szigethy, Eva
    Fiocchi, Claudio
    Colletti, Richard
    Otley, Anthony
    Amre, Devendra
    Ferry, George
    Czinn, Steven J.
    Splawski, Judy B.
    Oliva-Hemker, Maria
    Hyams, Jeffrey S.
    Faubion, William A.
    Kirschner, Barbara S.
    Dubinsky, Marla C.
    INFLAMMATORY BOWEL DISEASES, 2006, 12 (09) : 885 - 913
  • [22] The Treatment of Pediatric Inflammatory Bowel Disease
    Kim, Kyung Mo
    PEDIATRIC GASTROENTEROLOGY HEPATOLOGY & NUTRITION, 2008, 11 : 72 - 79
  • [23] Update in Pediatric Inflammatory Bowel Disease
    Rabizadeh, Shervin
    Dubinsky, Marla
    RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 2013, 39 (04) : 789 - +
  • [24] PEDIATRIC INFLAMMATORY BOWEL-DISEASE
    NOEL, RA
    FERRY, GD
    CURRENT OPINION IN GASTROENTEROLOGY, 1992, 8 (04) : 676 - 682
  • [25] Controversies in pediatric inflammatory bowel disease
    Cohen, MB
    Seidman, E
    Winter, H
    Colletti, RB
    Kirschner, B
    Balistreri, WF
    Grand, RJ
    INFLAMMATORY BOWEL DISEASES, 1998, 4 (03) : 203 - 227
  • [26] PEDIATRIC INFLAMMATORY BOWEL-DISEASE
    FERRY, GD
    NOEL, RA
    CURRENT OPINION IN GASTROENTEROLOGY, 1991, 7 (04) : 617 - 621
  • [27] Microbiota in Pediatric Inflammatory Bowel Disease
    Schwiertz, Andreas
    Jacobi, Manuela
    Frick, Julia-Stefanie
    Richter, Markus
    Rusch, Kerstin
    Koehler, Henrik
    JOURNAL OF PEDIATRICS, 2010, 157 (02): : 240 - U94
  • [28] Nutrition in Pediatric Inflammatory Bowel Disease
    Mallon, Daniel P.
    Suskind, David L.
    NUTRITION IN CLINICAL PRACTICE, 2010, 25 (04) : 335 - 339
  • [29] Inflammatory Bowel Disease in Pediatric Age
    Lee, Jee Hyun
    PEDIATRIC GASTROENTEROLOGY HEPATOLOGY & NUTRITION, 2011, 14 : S34 - S41
  • [30] Inflammatory bowel disease in pediatric patients
    Marx, G
    Seidman, EG
    CURRENT OPINION IN GASTROENTEROLOGY, 1999, 15 (04) : 322 - 325
12345