Biodegradable Ceramics Consisting of Hydroxyapatite for Orthopaedic Implants

被引:15
|
作者
Monsees, Thomas K. [1 ]
Azem, Funda Ak [2 ]
Cotrut, Cosmin Mihai [3 ,4 ]
Braic, Mariana [5 ]
Abdulgader, Radwan [1 ]
Pana, Iulian [5 ]
Birlik, Isil [2 ]
Kiss, Adrian [5 ]
Booysen, Robin [1 ]
Vladescu, Alina [4 ,5 ]
机构
[1] Univ Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
[2] Dokuz Eylul Univ, Engn Fac, Met & Mat Engn Dept, Tinaztepe Campus, TR-35397 Izmir, Turkey
[3] Univ Politehn Bucuresti, Fac Mat Sci & Engn, 313 Spl Independentei, Bucharest 060042, Romania
[4] Natl Res Tomsk Polytech Univ, Dept Expt Phys, Lenin Ave 43, Tomsk 634050, Russia
[5] Natl Inst Optoelect, 409 Atomistilor St, Magurele 77125, Romania
来源
COATINGS | 2017年 / 7卷 / 11期
关键词
hydroxyapatite; corrosion; roughness; nanoindentation; osteoblasts; magnetron sputtering; CALCIUM-PHOSPHATE COATINGS; MECHANICAL-PROPERTIES; CORROSION BEHAVIOR; THIN-FILMS; MAGNESIUM; TITANIUM; FTIR; BIOCOMPATIBILITY; PHOTOCATALYSIS; INDENTATION;
D O I
10.3390/coatings7110184
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
This study aims to analyze hydroxyapatite (HAP) coatings enriched with Mg and Ti prepared by a magnetron sputtering technique on Ti6Al4V substrate. For preparation of the coatings, three magnetron targets (HAP, MgO and TiO2) were simultaneously co-worked. The concentration of Mg added was varied by modifying the power applied to the MgO target. In all coatings, the Ti concentration was maintained constant by keeping the same cathode power fed during the whole deposition. The influence of different Mg dopant contents on the formation of phase, microstructure and morphology of the obtained Ti-doped HAP coatings were characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). Moreover, the effects of Mg addition upon corrosion, mechanical and biological properties were also investigated. Mg- and Ti-doped HAP coating obtained at low radio-frequency (RF) power fed to the MgO target provided material with high corrosion resistance compared to other coatings and bare alloy. A slight decrease in hardness of the coatings was found after the Mg addition, from 8.8 to 5.7 GPa. Also, the values of elastic modulus were decreased from 87 to 53 GPa, this being an advantage for biomedical applications. The coatings with low Mg concentration proved to have good deformation to yielding and higher plastic properties. Biological test results showed that the novel surfaces exhibited excellent properties for the adhesion and growth of bone cells. Moreover, early adherent vital cell numbers were significantly higher on both coatings compared to Ti6Al4V, suggesting that Mg ions may accelerate initial osteoblast adhesion and proliferation.
引用
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页数:15
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