Metformin attenuates palmitic acid-induced insulin resistance in L6 cells through the AMP-activated protein kinase/sterol regulatory element-binding protein-1c pathway

被引：33
|
作者：
Wu, Wenjun [1 ]
Tang, Sunyinyan [2 ]
Shi, Junfeng [3 ]
Yin, Wenwen [1 ]
Cao, Shu [1 ]
Bu, Ruifang [4 ]
Zhu, Dalong [1 ,2 ]
Bi, Yan [1 ,2 ]
机构：
[1] Nanjing Med Univ, Drum Tower Clin Med Coll, Dept Endocrinol, Nanjing 210008, Jiangsu, Peoples R China
[2] Nanjing Univ, Sch Med, Drum Tower Hosp, Dept Endocrinol, Nanjing 210008, Jiangsu, Peoples R China
[3] Nanjing Med Univ, Nanjing Hosp 1, Dept Oncol, Nanjing 210008, Jiangsu, Peoples R China
[4] Nanjing Med Univ, Wuxi Peoples Hosp, Dept Endocrinol, Wuxi, Jiangsu, Peoples R China
来源：
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE | 2015年 / 35卷 / 06期
基金：
中国国家自然科学基金; 中国博士后科学基金;
关键词：
metformin; AMP-activated protein kinase; sterol regulatory element-binding protein 1c; insulin resistance; L6; cells; SKELETAL-MUSCLE CELLS; NONALCOHOLIC FATTY LIVER; LIPID-ACCUMULATION; TRANSCRIPTION; SREBP-1C; SENSITIVITY; MECHANISM; KINASE; MICE; HOMEOSTASIS;
D O I：
10.3892/ijmm.2015.2187
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：1734 / 1740
页数：7
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