β-Cell Targeted Immune Suppressive PD-1 Bispecific Agonists: A Novel Approach to Treat Type 1 Diabetes

被引：0
|
作者：
Bossi, Giovanna
Curnock, Adam P.
Weber, Peter
Kumaran, Jyothi
Bawden, Lindsay J.
Figueiredo, Rita
Wiseman, Katherine E.
O'Dwyer, Ronan
Overton, David
Gonzalez, Veronica
Lucato, Christina M. A.
Page, Keith
Smith, Nicola
Whaley, Lorraine
Ghadbane, Hemza
Knight, David
Henderson, Emma
Hearty, Stephen
Mahon, Tara
Weber, Peter
机构：
来源：
DIABETES | 2021年 / 70卷
关键词：
D O I：
10.2337/db21-58-LB
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
58-LB
引用
收藏
页数：4
相关论文
共 50 条
  • [21] Immune Mechanisms and Pathways Targeted in Type 1 Diabetes
    Laura M. Jacobsen
    Brittney N. Newby
    Daniel J. Perry
    Amanda L. Posgai
    Michael J. Haller
    Todd M. Brusko
    Current Diabetes Reports, 2018, 18
  • [22] Immune Mechanisms and Pathways Targeted in Type 1 Diabetes
    Jacobsen, Laura M.
    Newby, Brittney N.
    Perry, Daniel J.
    Posgai, Amanda L.
    Haller, Michael J.
    Brusko, Todd M.
    CURRENT DIABETES REPORTS, 2018, 18 (10)
  • [23] Molecular scanning of the gene for programmed cell death-1 (PD-1) as a candidate for type 1 diabetes susceptibility
    不详
    ENDOCRINE JOURNAL, 2005, 52 : 143 - 143
  • [24] Assessing PDL-1 and PD-1 in NoneSmall Cell Lung Cancer: A Novel Immunoscore Approach
    Paulsen, Erna-Elise
    Kilvaer, Thomas K.
    Khanehkenari, Mehrdad Rakaee
    Al-Saad, Samer
    Hald, Sigurd M.
    Andersen, Sigve
    Richardsen, Elin
    Ness, Nora
    Busund, Lill-Tove
    Bremnes, Roy M.
    Donnem, Tom
    CLINICAL LUNG CANCER, 2017, 18 (02) : 220 - +
  • [25] Camrelizumab-targeting a novel PD-1 epitope to treat hepatocellular carcinoma
    Rakke, Yannick Sebastiaan
    Sprengers, Dave
    Kwekkeboom, Jaap
    IJzermans, Jan Nicolaas Maria
    ANNALS OF TRANSLATIONAL MEDICINE, 2020, 8 (23)
  • [26] Immune checkpoint molecule PD-1 acts as a novel biomarker for the pathological process of gestational diabetes mellitus
    Ye, Xiaoying
    Ju, Songwen
    Duan, Houquan
    Yao, Yongliang
    Wu, Jianfen
    Zhong, Shao
    Chen, Lei
    Cao, ShaSha
    Xu, Yongfang
    Zheng, Xiaocui
    Wang, Haiyan
    Ge, Yan
    Ju, Songguang
    BIOMARKERS IN MEDICINE, 2017, 11 (09) : 741 - 749
  • [27] Novel approach to restore β-cell function in type 1 diabetes
    Carter, Jeffrey D.
    Nunemaker, Craig S.
    Chen, Meng
    Kimble, Sarah D.
    Garmey, James
    Mirmira, Ragravendra G.
    Yang, Zandong
    Nadler, Jerry L.
    DIABETES, 2006, 55 : A106 - A106
  • [28] Gene therapy for type 1 diabetes: a novel approach for targeted treatment of autoimmunity
    Creusot, RJ
    Fathman, CG
    JOURNAL OF CLINICAL INVESTIGATION, 2004, 114 (07): : 892 - 894
  • [29] Expression of PD-1 and PD-L1 in Extramammary Paget Disease: Implications for Immune-Targeted Therapy
    Mauzo, Shakuntala H.
    Tetzlaff, Michael T.
    Milton, Denai R.
    Siroy, Alan E.
    Nagarajan, Priyadharsini
    Torres-Cabala, Carlos A.
    Ivan, Doina
    Curry, Jonathan L.
    Hudgens, Courtney W.
    Wargo, Jennifer A.
    Sahin, Aysegul A.
    Pettaway, Curtis A.
    Prieto, Victor G.
    Aung, Phyu P.
    CANCERS, 2019, 11 (06):
  • [30] Exclusion of PD-1 from the immune synapse: A novel strategy to modulate T cell function
    Hao, Luke Yi
    Lerrer, Shalom
    Paiola, Matthieu
    Moore, Emily K.
    Gartshteyn, Yevgeniya
    Song, Ruijiang
    Goeckeritz, Michael
    Black, Matilda J.
    Bukhari, Shoiab
    Hu, Xizi
    Mor, Adam
    MOLECULAR THERAPY ONCOLOGY, 2024, 32 (03):
12345