Dissection and rational engineering of the biosynthetic pathway to enacyloxin, a promising anti-Gram-negative antibiotic

被引：0

作者：

Masschelein, J. ^{[1
]}

Sydor, P. K. ^{[1
]}

Griffiths, D. ^{[1
]}

Valentic, T. R. ^{[2
,3
,4
]}

Gallo, A. ^{[1
]}

Jones, C. ^{[5
]}

Song, L. ^{[1
]}

Tsai, S. C. ^{[2
,3
,4
]}

Lewandowski, J. R. ^{[1
]}

Mahenthiralingam, E. ^{[5
]}

Challis, G. L. ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

[2] Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92697 USA

[3] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA

[4] Univ Calif Irvine, Dept Pharmaceut Sci, Irvine, CA 92697 USA

[5] Cardiff Univ, Cardiff Sch Biosci, Organisms & Environm Div, Cardiff CF10 3AT, S Glam, Wales

来源：

PLANTA MEDICA | 2016年 / 82卷

基金：

英国生物技术与生命科学研究理事会;

关键词：

Synthetic biology; enzymology; polyketide biosynthesis; Burkholderia; antibiotic; BACTERIA; IIA; BINDING; TU;

D O I：

10.1055/s-0036-1596129

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

SL22

引用

页数：2

共 41 条

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