Neo-clerodane diterpenoids from Scutellaria lateriflora

被引:28
|
作者
Bruno, M
Cruciata, M
Bondi, ML
Piozzi, F
de la Torre, MC
Rodríguez, B
Servettaz, O
机构
[1] Univ Palermo, Dipartimento Chim Organ E Paterno, I-90123 Palermo, Italy
[2] CNR, Ist Chim & Tecnol Prod Nat, I-90146 Palermo, Italy
[3] CSIC, Inst Quim Organ, E-28006 Madrid, Spain
[4] Univ Milan, Dipartimento Biol, I-20132 Milan, Italy
关键词
Scutellaria lateriflora; Labiatae; neo-clerodane diterpenes; scutelaterins A-C; ajugapitin; scutecyprol A;
D O I
10.1016/S0031-9422(97)01032-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Three new diterpenoids, scutelaterins A-C, have been isolated from Scutellaria lateriflora and their structures established as (11S,13S,16S)-2 beta,6 alpha,19-triacetoxy-4 alpha,18;11,16;15,16-triepoxy-neo-clerod-14-ene (scutelaterin A), (11S,13S,16S)-6 alpha,19-diacetoxy-2 beta-(2'-methyl)butyryloxy-4 alpha,18;11,16;15,16-triepoxy-neo-clerod-14-ene (scutelaterin B) and (11S,13S,15R and S)-6 alpha,19-diacetoxy-2 beta-(2'-methyl)butyryloxy-4 alpha,18;11,16;15,16- triepoxy-neo-clerodan-15-ol (scutelaterin C) by chemical and spectroscopic means. In addition, the already known neo-clerodanes ajugapitin and scutecyprol A were also found in the same source. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:687 / 691
页数:5
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