Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma

被引:8
|
作者
Quero, Laurent [1 ,2 ]
Labidi, Mouna [1 ]
Bollet, Marc [3 ]
Bommier, Come [2 ]
Guillerm, Sophie [1 ]
Hennequin, Christophe [1 ,2 ]
Thieblemont, Catherine [2 ,4 ]
机构
[1] St Louis Hosp, AP HP, Dept Radiat Oncol, 1 Ave Claude Vellefaux, F-75010 Paris, France
[2] Univ Paris, Fac Med, F-75005 Paris, France
[3] Hartmann Oncol Radiotherapy Grp, Dept Radiat Oncol, F-92044 Levallois Perret, France
[4] St Louis Hosp, AP HP, Hematooncol, DMU DHI, Paris, France
关键词
Radiotherapy; Mucosa-associated lymphoid tissue; MALT; Helicobacter pylori; Lymphoma; Review; MALT LYMPHOMA; HELICOBACTER-PYLORI; RADIATION-THERAPY; MULTICENTER; ERADICATION; OUTCOMES; STOMACH; EPIDEMIOLOGY; EXPERIENCE; RISK;
D O I
10.4251/wjgo.v13.i10.1453
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease which is often associated with Helicobacter pylori (H. pylori) infection. First-line treatment of stage IE and IIE localized gastric MALT lymphoma is based on the eradication of H. pylori. The presence of H. pylori resistance factors such as translocation t (11;18), peri-gastric lymph node involvement and the degree of tumor infiltration of the gastric wall; or lack of response to antibiotic therapy are two main indications to treat with definitive radiotherapy (RT). RT is an effective treatment in localized gastric MALT lymphoma. A moderate dose of 30 Gy allows a high cure rate while being well tolerated. After treatment, regular gastric endoscopic follow-up is necessary to detect a potential occurrence of gastric adenocarcinoma.
引用
收藏
页码:1453 / 1465
页数:13
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