Synthesis of alkaloid analogues from α-amino acids by one-pot radical decarboxylation/alkylation

被引：22

作者：

Boto, A ^{[1
]}

De León, Y ^{[1
]}

Gallardo, JA ^{[1
]}

Hernández, R ^{[1
]}

机构：

[1] CSIC, Inst Prod Nat & Agrobiol, San Cristobal la Laguna 38206, Spain

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 2005卷 / 16期

关键词：

alkaloids; amino acids; nitrogen heterocycles; radical reactions; spiro compounds;

D O I：

10.1002/ejoc.200500124

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A mild, one-pot methodology to obtain a-substituted nitrogen heterocycles from commercial amino acids is reported. This versatile procedure has been applied to the synthesis of different alkaloid analogues in good to excellent yields. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)

引用

页码：3461 / 3468

页数：8

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