Response rate to the vaccination with hepatitis b vaccine among cardiovascular health staff in Tehran

This descriptive cross-sectional study was designed and carried out among 260 hospital personnel working in educational and medical centers of Shahid Mustafa Khomeini hospital, Tehran, Iran in 2013. The demographic data of the subjects and questions related to the history of vaccination were also collected. Hepatitis B surface antibody (Anti-HBS) titration was carried out by ELISA. Finally, the relationships between different variables and hepatitis B antibody levels were evaluated. The results of the present study showed that 83.8% of the hospital personnel in Tehran, as the capital of Iran, showed a good response to hepatitis B vaccination, which was almost similar to the results of other studies conducted in the country. There was a significant relationship between the and smoking, the history of needlestick exposures and lower years of work experience, while anti-HBs titer of the hospital personnel was not statistically associated with BMI, age, gender, education level, occupation, interval since last vaccination, and injection method. Enhancing the level of protection in Cardiovascular health staff against hepatitis B virus can lead to a decrease in the incidence of infection cases among the hospital personnel. Therefore, it is essential to perform the primary vaccination followed by an assessment of the responsiveness to it. Therefore, the aim of this study was to investigate the effect of the demographic factors on the response rate to hepatitis B vaccination among hospital personnel in Tehran. The lower response rate to hepatitis B vaccination obtained in the present study compared to the global average necessitates further investigation on the hospital personnel dealing with the patients directly or indirectly in Tehran, therefore, it is essential to design large-scale plans to identify and treat at-risk individuals.