Synthesis of Cinnamaldehyde Hydroxyl Sulfonic Sodium and Its Anti-fungal Activity

In this experiment, cinnamon oil was used as the raw material to produce a water soluble derivative. Cinnamaldehyde, a major constituent of cinnamon oil, is easy to take place nucleophilic addition with saturated sodium bisulfite aqueous solution and generate sodium hydrogensulfite adduct-cinnamaldehyde hydroxyl sulfonic sodium, which has great water solubility, and the yield was 74.64%. The chemical structure of the product was identified by Fourier Transform Infrared Spectroscopy (FTIR). The anti-fungal activity of the product was determined by paper-disc method with wood decay fungi such as Trametes versicolor, Gloeophyllum trabeum and wood stain fungi such as Aspergillus niger, Paecilomyces Variotii and Paecilomyces lilacinus. The anti-fungal experiment results showed that the product has a little anti-fungal activity for the selected stain fungi, especially Aspergillus niger, but the antifungal activity of the product is not good. It has no anti-fungal activity for Trametes versicolor and only a little activity for Gloeophyllum trabeum. The result indicates that the aldehyde group plays an important role in the anti-fungal activity of cinnamaldehyde. Some derivatives without changing aldehyde group should be focused on in the future.