Prophylactic platelet transfusion in children with thrombocytopenic disorders: A retrospective review

被引:4
|
作者
Ferrara, M. [1 ]
Capozzi, L. [1 ]
Coppola, A. [1 ]
Save, G. [1 ]
Coppola, L. [1 ]
机构
[1] Naples Second Univ, Dept Pediat, I-80138 Naples, Italy
关键词
idiopathic thrombocytopenic purpura (ITP); X linked thrombocytopenia (XLT); Wiskott-Aldrich syndrome (WAS); aplastic anemia syndrome (AAS); Fanconi anemia (FA);
D O I
10.1080/10245330701255213
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The safety of low platelet thresholds for prophylactic transfusions was retrospectively evaluated in 673 children with various thrombocytopenic disorders. In patients with idiopathic thrombocytopenic purpura and X linked thrombocytopenia the threshold for the use of platelet transfusion was based on bleeding events rather than platelet count. In children with hypoproliferative thrombocytopenia and Wiskott - Aldrich syndrome, prophylactic platelet transfusions were used when the platelet count was <= 5000/ mu l in stable patients and > 10,000/ mu l in cases of bleeding or infections. The restrictive policy of platelet transfusions was shown to be proved safe in many thrombocytopenic disorders.
引用
收藏
页码:297 / 299
页数:3
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