Reaction of 4-aryl-2-hydroxy-4-oxo-2-butenoic acid N-(4-acetylaminosulfonylphenyl)amides with hydrazine hydrate and phenylhydrazine

被引：1
|
作者：
Gein, V. L. [1 ]
Bobrovskaya, O. V. [1 ]
Seliverstov, G. V. [1 ]
Slepukhin, P. A. [2 ,3 ]
机构：
[1] Minist Hlth Russian Federat, Perm State Pharmaceut Acad, Ul Polevaya 2, Perm 614990, Russia
[2] Russian Acad Sci, Ural Branch, Postovskii Inst Organ Synth, Ekaterinburg, Russia
[3] Ural Fed Univ, Ekaterinburg, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2016年 / 86卷 / 02期
关键词：
N-arylamides 4-aryl-2-hydroxy-4-oxo-2-butenoic acid; hydrazine; phenylhydrazine; pyrazole-3-carboxamides;
D O I：
10.1134/S107036321602016X
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Reaction of 4-aryl-2-hydroxy-4-oxo-2-butenoic acid N-(4-acetylaminosulfonylphenyl)amides with hydrazine hydrate and phenylhydrazine in acetic acid has afforded N-[4-(acetylaminosulfonyl)phenyl]-5-arylpyrazole-3-carboxamides.
引用
收藏
页码：300 / 304
页数：5
相关论文
共 50 条
  • [21] Synthesis and Analgesic and Antibacterial Activity of 5-aryl-4-aroyl-1-(4-acetylaminosulfonylphenyl)-3-hydroxy-3-pyrrolin-2-ones
    V. L. Gein
    O. V. Bobrovskaya
    G. V. Seliverstov
    R. R. Makhmudov
    V. V. Novikova
    Pharmaceutical Chemistry Journal, 2017, 51 : 187 - 190
  • [22] Synthesis, antimicrobial, and analgesic activity of 4-aryl-2-N-morpholino- 4-oxo-2-butenoic acids
    Koz'minykh V.O.
    Belyaev A.O.
    Koz'minykh E.N.
    Makhmudov R.R.
    Odegova T.F.
    Pharmaceutical Chemistry Journal, 2004, 38 (8) : 431 - 433
  • [23] 4-aryl-2-hydroxy-4-oxobut-2-enoic acids N-(2-pyridyl)amides in reactions with diazo compounds
    N. E. Gavrilova
    V. V. Zalesov
    N. A. Pulina
    Russian Journal of Organic Chemistry, 2008, 44 : 709 - 714
  • [24] 4-aryl-2-hydroxy-4-oxobut-2-enoic acids N-(2-pyridyl)amides in reactions with diazo compounds
    Gavrilova, N. E.
    Zalesov, V. V.
    Pulina, N. A.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2008, 44 (05) : 709 - 714
  • [25] Synthesis and intramolecular cyclization of N-substituted 2-amino-4-aryl-4-oxo-2-butenoic acids
    Rubtsov, AE
    Zalesov, VV
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2003, 39 (06) : 869 - 874
  • [26] Synthesis and Intramolecular Cyclization of N-Substituted 2-Amino-4-aryl-4-oxo-2-butenoic Acids
    A. E. Rubtsov
    V. V. Zalesov
    Russian Journal of Organic Chemistry, 2003, 39 : 869 - 874
  • [27] (E)-4-Aryl-4-oxo-2-butenoic acid amides, chalcone-aroylacrylic acid chimeras: Design, antiproliferative activity and inhibition of tubulin polymerization
    Vitorovic-Todorovic, Maja D.
    Eric-Nikolic, Aleksandra
    Kolundzija, Branka
    Hamel, Ernest
    Ristic, Slavica
    Juranic, Ivan O.
    Drakulic, Branko J.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 62 : 40 - 50
  • [28] Synthesis and biological evaluation of 2-imino-benzal-4-(2′-hydroxy aryl)-thiazoles and N-[4′(2"-hydroxy aryl)-thiazole]-4-aryl-2-azetidinones.
    Rahatgaonkar, AM
    ASIAN JOURNAL OF CHEMISTRY, 1999, 11 (04) : 1427 - 1430
  • [29] Antiproliferative (E)-4-aryl-4-oxo-2-butenoic Acid Phenylamides, the Chalcone-aroylacrylic Acid Chimera
    Kolundzija, B.
    Drakulic, B.
    Vitorovic-Todorovic, M.
    Stanojkovic, T.
    Matic, I.
    Juranic, Z.
    EUROPEAN JOURNAL OF CANCER, 2012, 48 : S224 - S224
  • [30] Reactivity of (E)-4-aryl-4-oxo-2-butenoic acid arylamides toward 2-mercaptoethanol. A LFER study
    Cvijetic, Ilija N.
    Vitorovic-Todorovic, Maja D.
    Juranic, Ivan O.
    Drakulic, Branko J.
    MONATSHEFTE FUR CHEMIE, 2013, 144 (12): : 1815 - 1824
12345