Regulatory T-cells and effects of anti-CTLA4 and anti-PD1 therapy in a transgenic murine model of neuroblastoma

被引:0
|
作者
Chan, Randall [1 ]
Shirinbak, Soheila [1 ]
Muthugounder, Sakunthala [1 ]
Hung, Long [1 ]
Gnanachandran, Janahan [1 ]
Hajidaniel, Michael [1 ]
Asgharzadeh, Shahab [1 ]
机构
[1] USC Childrens Hosp Los Angeles, Los Angeles, CA USA
关键词
D O I
10.1158/1538-7445.AM2014-5021
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
5021
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Anti-CTLA-4 generates memory T-cells with greater expansion and functionality than anti-PD-1
    Mok, Stephen
    Liu, Huey
    Anang, Nana-Ama A. S.
    Mancuso, James J.
    Cobanoglu, Didem Agac
    Allison, James P.
    CANCER RESEARCH, 2024, 84 (06)
  • [22] Cyclophosphamide depletes tumor infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma
    Webb, Emily R.
    Moreno-Vincente, Julia
    Easton, Alistair
    Lanati, Silvia
    Taylor, Martin
    James, Sonya
    Williams, Emily L.
    English, Vikki
    Penfold, Chris
    Beers, Stephen A.
    Gray, Juliet C.
    ISCIENCE, 2022, 25 (09)
  • [23] Rescue by radiotherapy and anti-CTLA4/PD-1 after failure of anti-PD-1 therapy in metastatic NSCLC patients: The RECLAIM study
    Bahce, I.
    Schneiders, F. L.
    Hashemi, S.
    Veltman, J.
    Daniels, H.
    Fransen, M.
    Radonic, T.
    Ulas, E.
    Houda, I.
    Barlo, N.
    Disselhorst, M.
    van Laren, M.
    Tiemessen, M.
    Tarasevych, S.
    van Haarst, J. M. M.
    van Tilburg, P.
    Kunst, P.
    Moons-Pasic, A.
    de Gruijl, T. D.
    Senan, S.
    ANNALS OF ONCOLOGY, 2022, 33 (07) : S1021 - S1021
  • [24] Tumor eradication in a murine model of glioma with vaccination and anti-CTLA-4 but not anti-PD-1
    Field, Cameron S.
    Hunn, Martin K.
    Ferguson, Peter M.
    Yagita, Hideo
    Hermans, Ian F.
    Ancelet, Lindsay R.
    CANCER IMMUNOLOGY RESEARCH, 2016, 4 (01)
  • [25] Effect of radiofrequency ablation (RFA) combined with anti-CTLA-4 and anti-PD1 in a preclinical melanoma model.
    Franco-Mahecha, Olga L.
    Christou, Anna
    Mauda-Havakuk, Michal
    Katti, Prateek
    Pritchard, William F.
    Karanian, John W.
    Wood, Bradford J.
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (08)
  • [26] Combination between a long-acting engineered cytokine (NKTR-214) and checkpoint inhibitors anti-CTLA4 or anti-PD1 in inurine tumor models
    Kantak, Seema S.
    Lee, Steve
    Addepalli, Murali
    Hoch, Ute
    Penax, Rhoneil
    Pena, Rhoneil
    Kirksey, Yolanda
    Charych, Deborah H.
    Doberstein, Stephen K.
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [27] Cutaneous adverse events in 155 patients with metastatic melanoma consecutively treated with anti-CTLA4 and anti-PD1 combination immunotherapy: Incidence, management, and clinical benefit
    Patel, Anisha B.
    Farooq, Sahira
    Welborn, Macartney
    Amaria, Rodabe N.
    Chon, Susan Y.
    Diab, Adi
    Oliva, Isabella C. Glitza
    Huen, Auris O.
    Li, Shirley Q.
    Nelson, Kelly C.
    Pacha, Omar
    Patel, Sapna P.
    Rapini, Ronald P.
    Tawbi, Hussein A.
    Wong, Michael K.
    McQuade, Jennifer
    Davies, Michael A.
    Haydu, Lauren E.
    CANCER, 2022, 128 (05) : 975 - 983
  • [28] Early T Cell Infiltration Correlates with Anti-CTLA4 Treatment Response in Murine Cancer Models
    Almonte, Andrew A.
    Cavic, George
    Carroll, Christina S. E.
    Neeman, Teresa
    Fahrer, Aude M.
    JOURNAL OF IMMUNOLOGY, 2023, 211 (12): : 1858 - 1867
  • [29] Durable remissions associated with anti-CTLA-4 and anti-PD1 checkpoint inhibitors in a single center
    Smit, T.
    Rapoport, B. L.
    Van Eeden, R. I.
    ANNALS OF ONCOLOGY, 2017, 28
  • [30] Anti-CTLA-4 and anti-PD-1 immunotherapies repress tumor progression in preclinical breast and colon model with independent regulatory T cells response
    Rupp, Tristan
    Genest, Laurie
    Babin, David
    Legrand, Christophe
    Hunault, Marion
    Froget, Guillaume
    Castagne, Vincent
    TRANSLATIONAL ONCOLOGY, 2022, 20