Selecting synaptic partners: GRASPing the role of UNC-6/netrin

被引：0
|
作者：
Ch'ng, QueeLim [1 ]
机构：
[1] Kings Coll London, MRC Ctr Dev Neurobiol, London SE1 1UL, England
来源：
BMC BIOLOGY | 2011年 / 9卷
基金：
英国惠康基金; 英国生物技术与生命科学研究理事会; 英国医学研究理事会;
关键词：
C-ELEGANS; UNC-6; MIGRATIONS; NETRINS;
D O I：
10.1186/1741-7007-9-43
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in Neural Development describes the use of a synapse-specific label in Caenorhabditis elegans to implicate local UNC-6/netrin signaling in this developmental process. Thus, as well as their well known roles in cell migration and axon guidance, UNC-6/netrin signals distinguish an appropriate synaptic partner from other potential targets.
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页数：3
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