Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance

被引:450
|
作者
Gouda, Sushanto [1 ]
Das, Gitishree [2 ]
Sen, Sandeep K. [3 ]
Shin, Han-Seung [4 ]
Patra, Jayanta Kumar [2 ]
机构
[1] AMITY Inst Wildlife Sci, Noida, India
[2] Dongguk Univ, Res Inst Biotechnol & Med Converged Sci, Seoul, Goyang, South Korea
[3] Natl Inst Technol Rourkela, Dept Biotechnol & Med Engn, Rourkela, India
[4] Dongguk Univ, Dept Food Sci & Biotechnol, Seoul, Goyang, South Korea
来源
关键词
bioactive compounds; endophytes; foodborne diseases; secondary metabolites; BACTERIAL ENDOPHYTES; NATURAL-PRODUCTS; PLANTS; FUNGI; IDENTIFICATION; ANTIBIOTICS; DIVERSITY; TERM; GUT;
D O I
10.3389/fmicb.2016.01538
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Endophytes are an endosymbiotic group of microorganisms that colonize in plants and microbes that can be readily isolated from any microbial or plant growth medium. They act as reservoirs of novel bioactive secondary metabolites, such as alkaloids, phenolic acids, quinones, steroids, saponins, tannins, and terpenoids that serve as a potential candidate for antimicrobial, anti-insect, anticancer and many more properties. While plant sources are being extensively explored for new chemical entities for therapeutic purposes, endophytic microbes also constitute an important source for drug discovery. This review aims to comprehend the contribution and uses of endophytes as an impending source of drugs against various forms of diseases and other possible medicinal use.
引用
收藏
页数:8
相关论文
共 50 条
  • [31] Plants as the Extended Phenotype of Endophytes-The Actual Source of Bioactive Compounds
    Rutkowska, Natalia
    Drozdzynski, Piotr
    Ryngajllo, Malgorzata
    Marchut-Mikolajczyk, Olga
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (12)
  • [32] Fungal Endophytes: an Accessible Source of Bioactive Compounds with Potential Anticancer Activity
    Rai, Nilesh
    Gupta, Priyamvada
    Keshri, Priyanka Kumari
    Verma, Ashish
    Mishra, Pradeep
    Kumar, Deepak
    Kumar, Ajay
    Singh, Santosh Kumar
    Gautam, Vibhav
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2022, 194 (07) : 3296 - 3319
  • [33] Chemical elicitation as an avenue for discovery of bioactive compounds from fungal endophytes
    Munusamy, Madhaiyan
    Ching, Kuan Chieh
    Yang, Lay Kien
    Crasta, Sharon
    Gakuubi, Martin Muthee
    Chee, Zhao Yan
    Wibowo, Mario
    Leong, Chung Yan
    Kanagasundaram, Yoganathan
    Ng, Siew Bee
    FRONTIERS IN CHEMISTRY, 2022, 10
  • [34] Novel bioactive compounds produced by endophytes extracted from Fragaria vesca
    Ross, Jeannette
    Halling, Merrill
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
  • [35] Marine algae: A treasure trove of bioactive anti-inflammatory compounds
    Ghallab, Dina S.
    Ibrahim, Reham S.
    Mohyeldin, Mohamed M.
    Shawky, Eman
    MARINE POLLUTION BULLETIN, 2024, 199
  • [36] Strategies on biosynthesis and production of bioactive compounds in medicinal plants
    Guo, Miaoxian
    Lv, Haizhou
    Chen, Hongyu
    Dong, Shuting
    Zhang, Jianhong
    Liu, Wanjing
    He, Liu
    Ma, Yimian
    Yu, Hua
    Chen, Shilin
    Luo, Hongmei
    CHINESE HERBAL MEDICINES, 2024, 16 (01) : 13 - 26
  • [37] The Effects of Medicinal Plants and Bioactive Natural Compounds on Homocysteine
    Atazadegan, Mohammad Amin
    Bagherniya, Mohammad
    Askari, Gholamreza
    Tasbandi, Aida
    Sahebkar, Amirhossein
    MOLECULES, 2021, 26 (11):
  • [38] EFFECT OF GAMMA IRRADIATION ON BIOACTIVE COMPOUNDS OF MEDICINAL PLANTS
    Radomir, Ana-Maria
    SCIENTIFIC PAPERS-SERIES B-HORTICULTURE, 2021, 65 (02): : 292 - 299
  • [39] Medicinal Plant Centipeda Minima: A Resource of Bioactive Compounds
    Nguyen Thi Thuy Linh
    Nguyen Thi Thu Ha
    Nguyen Thanh Tra
    Le Thi Tu Anh
    Nguyen Van Tuyen
    Ninh The Son
    MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 21 (03) : 273 - 287
  • [40] A review on importance of bioactive compounds of medicinal plants in treating idiopathic pulmonary fibrosis (special emphasis on isoquinoline alkaloids)
    Sai Sushma Dudala
    T. C. Venkateswarulu
    Sushma Chandulee Kancharla
    Vidya Prabhakar Kodali
    D. John Babu
    Future Journal of Pharmaceutical Sciences, 7