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Algorithms for the treatment of motor problems in Parkinson's disease
被引:45
|作者:
Dietrichs, E.
[1
,2
]
Odin, P.
[3
,4
]
机构:
[1] Oslo Univ Hosp, Dept Neurol, Oslo, Norway
[2] Univ Oslo, Oslo, Norway
[3] Lund Univ, Skane Univ Hosp, Dept Neurol, Lund, Sweden
[4] Klinikum Bremerhaven, Dept Neurol, Bremerhaven, Germany
来源:
关键词:
apomorphine;
deep brain stimulation;
levodopa-carbidopa intestinal gel;
motor complications;
Parkinson's disease;
treatment;
DEEP-BRAIN-STIMULATION;
CARBIDOPA INTESTINAL GEL;
QUALITY STANDARDS SUBCOMMITTEE;
RANDOMIZED CONTROLLED-TRIAL;
5-YEAR FOLLOW-UP;
SUBTHALAMIC NUCLEUS;
APOMORPHINE INFUSION;
PRACTICE PARAMETER;
DOPAMINE AGONISTS;
LEVODOPA INFUSION;
D O I:
10.1111/ane.12733
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Several different strategies are effective for medical treatment of motor problems in Parkinson's disease (PD). Many guidelines and evidence-based reviews are available, but there is no documentation or consensus in favor of just one treatment strategy. This review presents two algorithms that may be helpful when deciding how to treat a PD patient at various stages of the disease. The first algorithm suggests one way to treat PD from the first onset of motor symptoms. It is largely based on treatment recommendations from the Scandinavian countries and Germany. The other algorithm is meant as assistance for choosing among the different device-aided treatments for advanced PD. There is not sufficient comparative data to recommend one particular line of treatment, neither in early PD nor in advanced disease with motor complications. Individualized treatment is needed for each patient. The current algorithms only represent an alternative for aiding treatment decisions.
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页码:378 / 385
页数:8
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