Synthesis of 2-substituted benzimidazoles by iodine-mediated condensation of orthoesters with 1,2-phenylenediamines

被引：67

作者：

Zhang, Zhan-Hui ^{[1
]}

Li, Jian-Jiong ^{[1
]}

Gao, Yuan-Zhe ^{[1
]}

Liu, Yu-Heng ^{[1
]}

机构：

[1] Hebei Normal Univ, Coll Chem & Mat Sci, Shijiazhuang 050091, Peoples R China

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 44卷 / 06期

关键词：

D O I：

10.1002/jhet.5570440642

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Iodine was found to be an efficient catalyst for the synthesis of 2-substituted benzimidazoles by the condensation of orthoesters and 1,2-phenylenediamines in good to excellent yields under mild reaction conditions.

引用

页码：1509 / 1512

页数：4

共 50 条

[21] Synthesis of several new 2-substituted benzimidazoles
Han, Xiao-Feng
Chen, Man-Man
Zhou, Zhi-Mimg
JOURNAL OF CHEMICAL RESEARCH, 2015, (07) : 407 - 409
[22] Practical oxone-mediated high-throughput solution-phase synthesis of benzimidazoles from 1,2-phenylenediamines and aldehydes and its application to preparative scale synthesis.
Beaulieu, PL
Haché, B
von Moos, E
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 226 : U176 - U176
[23] Water-Mediated Synthesis of 2-Substituted Benzimidazoles by Boric Acid and Glycerol
Mukhopadhyay, Chhanda
Tapaswi, Pradip Kumar
Butcher, Ray J.
AUSTRALIAN JOURNAL OF CHEMISTRY, 2009, 62 (02) : 140 - 144
[24] Nitroxide radicals of some N-phenyl substituted 1,4-and 1,2-phenylenediamines
Burian, M
Omelka, L
Ondrásová, S
Brezová, V
MONATSHEFTE FUR CHEMIE, 2003, 134 (04): : 501 - 508
[25] Copper-Catalyzed Cascade Reactions of Substituted 4-Iodopyrazolecarbaldehydes with 1,2-Phenylenediamines and 2-Aminophenols
Nayak, Maloy
Batra, Sanjay
ADVANCED SYNTHESIS & CATALYSIS, 2010, 352 (18) : 3431 - 3437
[26] DERIVATIVES OF 2,3-DIHYDRO-1H-1,5-BENZODIAZEPINE FROM SUBSTITUTED 1,2-PHENYLENEDIAMINES AND ACETYLARENES
ORLOV, VD
DESENKO, SM
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1985, (12): : 1673 - 1678
[27] Synthesis and biological evaluation of some 2-substituted benzimidazoles
Gupta, SK
Imran, M
Rehman, ZU
Khan, SA
ASIAN JOURNAL OF CHEMISTRY, 2005, 17 (04) : 2741 - 2747
[28] SYNTHESIS AND POLYMERIZATION OF SOME OPTICALLY ACTIVE 2-SUBSTITUTED AND 1,2-SUBSTITUTED BUTADIENES
JANOVIC, Z
FLES, D
JOURNAL OF POLYMER SCIENCE PART A-1-POLYMER CHEMISTRY, 1971, 9 (04): : 1103 - &
[29] Sulfur-mediated annulation of 1,2-phenylenediamines towards benzofuro- and benzothieno-quinoxalines
Loan T Tran
Tuan H Ho
Nhu T A Phan
Tung T Nguyen
Nam T S Phan
ORGANIC & BIOMOLECULAR CHEMISTRY, 2020, 18 (29) : 5652 - 5659
[30] Facile synthesis of 2-substituted 1,2-dihydro-1-naphthols and 2-substituted 1-naphthols
Chen, CL
Martin, SF
ORGANIC LETTERS, 2004, 6 (20) : 3581 - 3584

← 1 2 3 4 5 →