Fullerene C60 and graphene photosensibiles for photodynamic virus inactivation

被引：1

作者：

Belousova, I. ^{[1
,2
]}

Hvorostovsky, A. ^{[1
,3
,6
]}

Kiselev, V. ^{[1
,2
]}

Zarubaev, V. ^{[2
]}

Kiselev, O. ^{[2
]}

Piotrovsky, L. ^{[2
,4
]}

Anfimov, P. ^{[2
,4
]}

Krisko, T. ^{[2
,4
]}

Muraviova, T. ^{[1
,4
]}

Rylkov, V. ^{[1
,4
]}

Starodubzev, A. ^{[2
,4
]}

Sirotkin, A. ^{[2
,4
]}

Grishkanich, A. ^{[1
,3
,6
]}

Kudashev, I. ^{[6
]}

Kancer, A. ^{[1
]}

Kustikova, M. ^{[1
]}

Bykovskaya, E. ^{[1
]}

Mayurova, A. ^{[1
]}

Stupnikov, A. ^{[1
]}

Ruzankina, J. ^{[1
]}

Afanasyev, M. ^{[4
]}

Lukyanov, N. ^{[1
]}

Redka, D. ^{[3
,6
]}

Paklinov, N. ^{[5
,6
]}

机构：

[1] ITMO Univ, St Petersburg, Russia

[2] State Opt Inst SI Vavilov GOI, St Petersburg, Russia

[3] St Petersburg State Electrotech Univ, St Petersburg, Russia

[4] Res Inst Influenza, St Petersburg, Russia

[5] Tyumen Ind Univ, Fed State Budget Educ Inst Higher Educ, Tyumen, Russia

[6] LLC Lazertrek, Moscow, Russia

来源：

OPTICAL INTERACTIONS WITH TISSUE AND CELLS XXIX | 2018年 / 10492卷

关键词：

pathogenic viruses; photodynamic inactivation of viruses; graphene photosensibiles; Fullerene C60; SINGLET OXYGEN; CONTAINING MEDIA; GENERATION;

D O I：

10.1117/12.2294593

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A solid-phase photosensitizer based on aggregated C60 fullerene and graphene oxide for photodynamic inactivation of pathogens in biological fluids was studied. The most promising technologies of inactivation include the photodynamic effect, which consists in the inactivation of infectious agents by active oxygen forms (including singlet oxygen), formed when light is activated by the photosensitizer introduced into the plasma. Research shows features of solid-phase systems based on graphene and fullerene C60 oxide, which is a combination of an effective inactivating pathogens (for example, influenza viruses) reactive oxygen species formed upon irradiation of the photosensitizer in aqueous and biological fluids, a high photostability fullerene coatings and the possibility of full recovery photosensitizer from the biological environment after the photodynamic action.

引用

页数：9

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