Ep-CAM overexpression in breast cancer as a predictor of survival

被引：245
|
作者：
Gastl, G [1 ]
Spizzo, G
Obrist, P
Dünser, M
Mikuz, G
机构：
[1] Univ Innsbruck, Div Haematol & Oncol, A-6020 Innsbruck, Austria
[2] Univ Innsbruck, Inst Pathol, A-6020 Innsbruck, Austria
[3] Univ Innsbruck, Dept Surg, A-6020 Innsbruck, Austria
来源：
LANCET | 2000年 / 356卷 / 9246期
关键词：
D O I：
10.1016/S0140-6736(00)03312-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The epithelial glycoprotein Ep-CAM is overexpressed in colon cancer and breast cancer. We assessed the frequency and prognostic significance of Ep-CAM in tissue specimens from 205 patients with invasive breast cancer, by immunohistochemical staining with a monoclonal antibody specific for the Ep-CAM antigen. Ep-CAM overexpression was found in 35.6% of samples and was associated with poor disease-free and overall survival.
引用
收藏
页码：1981 / 1982
页数：2
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