Biotransformation of vermitaline by Cunninghamella echinulata

被引：9
|
作者：
Lu, Yi-Feng [1 ,2 ]
Chen, Ke-Yu [1 ]
Li, Hui-Liang [1 ]
Pei, Yue-Hu [2 ]
Liu, Run-Hui [1 ]
Zhang, Wei-Dong [1 ,3 ]
机构：
[1] Second Mil Med Univ, Sch Pharm, Shanghai 200433, Peoples R China
[2] Shenyang Pharmaceut Univ, Dept Nat Med Chem, Sch Tradit Chinese Mat Med 49, Shenyang 110016, Peoples R China
[3] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
来源：
HELVETICA CHIMICA ACTA | 2008年 / 91卷 / 05期
关键词：
D O I：
10.1002/hlca.200890083
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Biotransformation of vermitaline (1) by Cunninghamella echinulata (ACCC 30369) was carried out. Four biotransformation products were obtained and three of them were characterized as new compounds. On the basis of their NMR and mass-spectral data, their structures were characterized as 7 alpha-hydroxyrubijervine (2), 7 alpha-hydroxyrubijervine-7-O-beta-D-galactofuranoside (3), 7 alpha-hydroxyvermitaline (4), and 7 alpha-hydroxyvermitaline-7-O-beta-D-galactofuranoside (5).
引用
收藏
页码：819 / 824
页数：6
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