Mesenchymal Autologous Stem Cells

被引:2
|
作者
Falavigna, Asdrubal [1 ]
da Costa, Jaderson Costa [2 ,3 ]
机构
[1] Univ Caxias do Sul, Sch Med, Dept Neurosurg, Caxias Do Sul, Brazil
[2] Pontificia Univ Catolica Rio Grande do Sul, Neurol Serv, Porto Alegre, RS, Brazil
[3] Pontificia Univ Catolica Rio Grande do Sul, Inst Cerebro, Porto Alegre, RS, Brazil
关键词
Cell transplantation; Clinical translations; Mesenchymal stem cells; Neuronal differentiation; Spinal cord injury; MARROW STROMAL CELLS; SPINAL-CORD-INJURY; HUMAN BONE-MARROW; TRAUMATIC BRAIN-INJURY; PROMOTE FUNCTIONAL RECOVERY; MYELIN-ASSOCIATED GLYCOPROTEIN; CEREBRAL-ISCHEMIA MODEL; CHRONIC PARAPLEGIC RATS; HUMAN ADIPOSE-TISSUE; IN-VIVO;
D O I
10.1016/j.wneu.2013.02.026
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The use of cell-based therapies for spinal cord injuries has recently gained prominence as a potential therapy or component of a combination strategy. Experimental and clinical studies have been performed using mesenchymal stem cell therapy to treat spinal cord injuries with encouraging results. However, there have been reports on the adverse effects of these stem cell-based therapies, especially in the context of tumor modulation. This article surveys the literature relevant to the potential of mesenchymal autologous stem cells for spinal cord injuries and their clinical implications.
引用
收藏
页码:236 / 250
页数:15
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