The relationship between the work of bioethicists and that of disability studies scholars and activists is only now beginning to be explored. 1,2 This special issue of Theoretical Medicine and Bioethics is an attempt to rectify that situation. We believe that one should not see disability as just one more topic for bioethicists to take up, much as they would take up the ethical issues involved with identifying a correlation between a particular gene and certain diseases. Rather, bioethics must approach disability as new land that is inextricably linked with traditional terrain yet, somehow, foreign. The essays in this special issue are an important step in that direction.