Stochasticity versus determinism in development: a false dichotomy?

被引：32

作者：

Zernicka-Goetz, Magdalena ^{[1
]}

Huang, Sui ^{[2
]}

机构：

[1] Univ Cambridge, Gurdon Inst, Cambridge CB2 1QN, England

[2] Univ Calgary, Inst Biocomplex & Informat, Calgary, AB T2N 1N4, Canada

来源：

NATURE REVIEWS GENETICS | 2010年 / 11卷 / 11期

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

INNER CELL MASS; MOUSE; SPECIFICATION; TROPHECTODERM; POLARITY; NOISE; FATE; CDX2;

D O I：

10.1038/nrg2886

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Gene expression noise can suggest a role for stochasticity during development. But Magdalena Zernicka-Goetz and Sui Huang argue that care should be taken in data interpretation and language use before labelling developmental events as 'random'.

引用

页码：743 / 744

页数：2

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