Stochasticity versus determinism in development: a false dichotomy?

被引：32
|
作者：
Zernicka-Goetz, Magdalena [1 ]
Huang, Sui [2 ]
机构：
[1] Univ Cambridge, Gurdon Inst, Cambridge CB2 1QN, England
[2] Univ Calgary, Inst Biocomplex & Informat, Calgary, AB T2N 1N4, Canada
来源：
NATURE REVIEWS GENETICS | 2010年 / 11卷 / 11期
基金：
英国医学研究理事会; 英国惠康基金;
关键词：
INNER CELL MASS; MOUSE; SPECIFICATION; TROPHECTODERM; POLARITY; NOISE; FATE; CDX2;
D O I：
10.1038/nrg2886
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Gene expression noise can suggest a role for stochasticity during development. But Magdalena Zernicka-Goetz and Sui Huang argue that care should be taken in data interpretation and language use before labelling developmental events as 'random'.
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页码：743 / 744
页数：2
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