A novel missense mutation in the homeodomain of the hepatocyte nuclear factor-1α/maturity-onset diabetes of the young 3 in a Japanese early-onset type 2 diabetic patient and time-course of glucose-stimulated insulin secretion

被引：12
|
作者：
Awata, T
Kurihara, S
Inoue, K
Inoue, I
Takei, S
Ishii, C
Negishi, K
Namai, K
Kanazawa, Y
Kuzuya, T
Katayama, S
机构：
[1] Saitama Med Sch, Dept Internal Med 4, Moroyama, Saitama 3500495, Japan
[2] Jichi Med Sch, Omiya Med Ctr, Omiya, Saitama, Japan
来源：
DIABETES CARE | 1998年 / 21卷 / 09期
关键词：
D O I：
10.2337/diacare.21.9.1569
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1569 / 1571
页数：3
相关论文
共 50 条
  • [31] Identification of a novel hepatocyte nuclear factor-1 alpha (HNF1A) variant in maturity onset diabetes of the young type 3 (HNF1A-MODY)
    Verma, Megha
    Stone, Stephen, I
    ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS, 2022, 2022
  • [32] A NOVEL MUTATION (G554fsX556) OF HEPATOCYTE NUCLEAR FACTOR-1ALPHA IN THAI PATIENTS WITH MATURITY-ONSET DIABETES OF THE YOUNG (MODY)
    Kooptiwut, Suwattanee
    Sujjitjoon, Jatuporn
    Plengvidhya, Nattachet
    Banchuin, Napatawn
    Furuta, Hiroto
    Yenchitsomanus, Pa-thai
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, 59 : 330 - 330
  • [33] A novel mutation in the hepatocyte nuclear factor-1β gene in maturity onset diabetes of the young 5 with multiple renal cysts and pancreas hypogenesis: A case report
    Lv, You
    Li, Zhuo
    He, Kan
    Gao, Ying
    Xiao, Xianchao
    Liu, Yujia
    Wang, Guixia
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 14 (04) : 3131 - 3136
  • [34] A prevalent amino acid polymorphism at codon 98 (Ala98Val) of the hepatocyte nuclear factor-1α is associated with maturity-onset diabetes of the young and younger age at onset of type 2 diabetes in Asian Indians
    Anuradha, S
    Radha, V
    Deepa, R
    Hansen, T
    Carstensen, B
    Pedersen, O
    Mohan, V
    DIABETES CARE, 2005, 28 (10) : 2430 - 2435
  • [35] Splice site mutation in the hepatocyte nuclear factor-1β Gene, IVS2nt + 1G > A, associated with maturity-onset diabetes of the young, renal dysplasia and bicornuate uterus
    Diabetologia, 2001, 44 (3) : 387 - 388
  • [36] Allelic drop-out in exon 2 of the hepatocyte nuclear factor-1α gene hinders the identification of mutations in three families with maturity-onset diabetes of the young
    Ellard, S
    Bulman, MP
    Frayling, TM
    Allen, LIS
    Dronsfield, MJ
    Tack, CGJ
    Hattersley, AT
    DIABETES, 1999, 48 (04) : 921 - 923
  • [37] Time-course changes in clinical features of early-onset Japanese type 1 and type 2 diabetes: TWMU hospital-based study
    Uchigata, Yasuko
    Otani, Toshika
    Takaike, Hiroko
    Miura, Junnosuke
    Osawa, Mari
    Tukahara, Sachie
    Kasahara, Tadasu
    Iwamoto, Yasuhiko
    DIABETES RESEARCH AND CLINICAL PRACTICE, 2008, 82 (01) : 80 - 86
  • [38] In silico and in vitro analyses of the pathological relevance of the R258H mutation of hepatocyte nuclear factor 4α identified in maturity-onset diabetes of the young type 1
    Sugawara, Kenji
    Nomura, Kazuhiro
    Okada, Yuko
    Sugano, Aki
    Matsumoto, Masaaki
    Takarada, Toru
    Takeuchi, Atsuko
    Awano, Hiroyuki
    Hirota, Yushi
    Nishio, Hisahide
    Takaoka, Yutaka
    Ogawa, Wataru
    JOURNAL OF DIABETES INVESTIGATION, 2019, 10 (03) : 680 - 684
  • [39] Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1α-deficient mice -: A mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3)
    Boileau, P
    Wolfrum, C
    Shih, DQ
    Yang, TA
    Wolkoff, AW
    Stoffel, M
    DIABETES, 2002, 51 : S343 - S348
  • [40] Identification of a missense mutation (P33T) in the insulin promoter factor-1 (IPF-1) gene in an Italian patient with early onset type 2 diabetes
    Gragnoli, C
    Lindner, T
    Chiaromonte, F
    Colasurdo, L
    D'Antonio, T
    Gragnoli, F
    Gragnoli, G
    Manetti, E
    Signorini, AM
    Marozzi, G
    DIABETOLOGIA, 1998, 41 : A106 - A106
12345