Regularities of the location of genes having different functions and of some other nucleotide sequences in the bacterial chromosome

被引：3
|
作者：
Prozorov, A. A. [1 ]
机构：
[1] Russian Acad Sci, NI Vavilov Gen Genet Res Inst, Moscow 117809, Russia
来源：
MICROBIOLOGY | 2007年 / 76卷 / 04期
关键词：
chromosome; replichores; replication; leading and lagging DNA strand; vitally important genes;
D O I：
10.1134/S0026261707040017
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The review considers the results of genomic research performed over the last decade that shed light on the location in the bacterial chromosomes of genes having different functions. A tendency towards polarity of the chromosome composition is observed: vitally important genes tend to be concentrated in the region of replication origin (oriC), and their concentration decreases toward the region of replication termination (terC). An oppositely directed polarity (an increase near the terC region) is observed for the distribution of certain oligonucleotides involved in the process of chromosome recombination and segregation.
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页码：383 / 392
页数：10
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