Dipeptidyl peptidase inhibitor PT-100 suppresses tumor growth in vivo and enhances chemotherapy in mice.

被引：0
|
作者：
Adams, S [1 ]
Miller, GT [1 ]
Jones, B [1 ]
机构：
[1] Point Therapeut Inc, Boston, MA USA
来源：
CLINICAL CANCER RESEARCH | 2003年 / 9卷 / 16期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：6229S / 6230S
页数：2
相关论文
共 50 条
  • [31] Rho-kinase inhibitor suppresses tumor growth and intrahepatic metastases of hepatocellular carcinoma - In vitro and in vivo study.
    Xue, F
    Takahara, T
    Nonome, K
    Yata, Y
    Shinno, E
    Watanabe, A
    HEPATOLOGY, 2003, 38 (04) : 400A - 400A
  • [32] VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
    Elizabeth A Harrington
    David Bebbington
    Jeff Moore
    Richele K Rasmussen
    Abi O Ajose-Adeogun
    Tomoko Nakayama
    Joanne A Graham
    Cecile Demur
    Thierry Hercend
    Anita Diu-Hercend
    Michael Su
    Julian M C Golec
    Karen M Miller
    Nature Medicine, 2004, 10 : 262 - 267
  • [33] VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
    Harrington, EA
    Bebbington, D
    Moore, J
    Rasmussen, RK
    Ajose-Adeogun, AO
    Nakayama, T
    Graham, JA
    Demur, C
    Hercend, T
    Diu-Hercend, A
    Su, M
    Golec, JMC
    Miller, KM
    NATURE MEDICINE, 2004, 10 (03) : 262 - 267
  • [34] MK-8033, a selective c-Met/Ron inhibitor, suppresses tumor cell growth in vitro and in vivo
    Harrington, Elizabeth
    Chan, Grace
    Chenard, Melissa
    Dahlberg, William
    Davis, Lenora
    Deshmukh, Sujal
    Dinsmore, Christopher
    Efferson, Clayton
    Hang, Gaozhen
    Hatch, Harold
    Kohl, Nancy
    Kunil, Kaiko
    Lu, Wei
    Lutterbach, Bart
    Majumder, Pradip
    Northrup, Alan
    Qu, Xianlu
    Reilly, John
    Rosenstein, Craig
    Szewczak, Alexander
    Tammam, Jennifer
    Ware, Christopher
    Zheng, Qinwen
    Pan, Bo-Sheng
    CANCER RESEARCH, 2009, 69
  • [35] A novel ligand-independent peptide inhibitor of TREM-1 attenuates inflammation and suppresses tumor growth in mice
    Sigalov, Alexander B.
    CANCER RESEARCH, 2014, 74 (19)
  • [36] Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Suppresses CXCL5 and Sdf-1 and Does Not Accelerate Intestinal Neoplasia Formation in APCMIN/+ Mice Fed a High Fat Diet
    Fujiwara, Kaori
    Inoue, Takuya
    Yorifuji, Naoki
    Iguchi, Munetaka
    Okada, Toshihiko
    Kakimoto, Kazuki
    Nouda, Sadaharu
    Kawakami, Ken
    Abe, Yosuke
    Takeuchi, Toshihisa
    Higuchi, Kazuhide
    GASTROENTEROLOGY, 2015, 148 (04) : S577 - S577
  • [37] An original synthetic antioxidant of combined action based on monophenol effectively suppresses tumor growth in vivo and combats side effects of chemotherapy
    Menshchikova, Elena
    Khrapova, Marina
    Petrova, Ekaterina
    Serykh, Anastasiya
    Romakh, Lidiya
    Kandalintseva, Natalya
    FREE RADICAL BIOLOGY AND MEDICINE, 2024, 224
  • [38] GSK1838705A, an IGF-1R inhibitor, inhibits glioma cell proliferation and suppresses tumor growth in vivo
    Zhou, Xiang
    Shen, Fazheng
    Ma, Pengju
    Hui, Hongyan
    Pei, Sujuan
    Chen, Ming
    Wang, Zhongwei
    Zhou, Wenke
    Jin, Baozhe
    MOLECULAR MEDICINE REPORTS, 2015, 12 (04) : 5641 - 5646
  • [39] DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
    Meng-di Dai
    Yue-liang Wang
    Jun Fan
    Yang Dai
    Yin-chun Ji
    Yi-ming Sun
    Xia Peng
    Lan-lan Li
    Yu-ming Wang
    Wen-hu Duan
    Jian Ding
    Jing Ai
    Acta Pharmacologica Sinica, 2021, 42 : 1498 - 1506
  • [40] SR-4370, a potent and selective inhibitor of class I HDACs, suppresses AR signaling and in vivo prostate tumor growth
    Mahmud, Iqbal
    Tian, Guimei
    Wang, Jia
    Stowe, Ryan
    Huo, Zhiguang
    Zhang, Yushan
    Purayil, Hamsa Thayek
    Helm, Eric
    Drashansky, Theodore
    Avram, Dorina
    Daaka, Yehia
    Roush, William R.
    Liao, Daiqing
    CANCER RESEARCH, 2019, 79 (13)
12345