FKBP5 Regulates HPA Axis Activity by Fine Tuning the Mineralocorticoid/Glucocorticoid Receptor Balance in the Hippocampus

被引：0
|
作者：
Hartmann, Jakob [1 ]
Klengel, Claudia [1 ]
McCullough, Kenneth [1 ]
Klengel, Torsten [1 ]
Joels, Marian [1 ]
Dudek, Serena [1 ]
Sarabdjitsingh, Angela [1 ]
Schmidt, Mathias V. [1 ]
Ressler, Kerry [1 ]
机构：
[1] Harvard Univ, McLean Hosp, Sch Med, Belmont, MA USA
来源：
NEUROPSYCHOPHARMACOLOGY | 2019年 / 44卷 / SUPPL 1期
关键词：
HPA Axis; Glucocorticoid Receptor; Mineralocorticoid Receptor; FKBP5; Hippocampus;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
M79
引用
收藏
页码：118 / 119
页数：2
相关论文
共 50 条
  • [31] Methylation and expression of glucocorticoid receptor exon-1 variants and FKBP5 in teenage suicide-completers
    Hooriyah S. Rizavi
    Omar S. Khan
    Hui Zhang
    Runa Bhaumik
    Dennis R. Grayson
    Ghanshyam N. Pandey
    Translational Psychiatry, 13
  • [32] Methylation and expression of glucocorticoid receptor exon-1 variants and FKBP5 in teenage suicide-completers
    Rizavi, Hooriyah S. S.
    Khan, Omar S. S.
    Zhang, Hui
    Bhaumik, Runa
    Grayson, Dennis R. R.
    Pandey, Ghanshyam N. N.
    TRANSLATIONAL PSYCHIATRY, 2023, 13 (01)
  • [33] Sex-dependent association of DNA methylation of HPA axis-related gene FKBP5 with obsessive-compulsive disorder
    Seo, Jun Ho
    Kim, Shin Tae
    Jeon, Sumoa
    Kang, Jee In
    Kim, Se Joo
    PSYCHONEUROENDOCRINOLOGY, 2023, 158
  • [34] Decreased glucocorticoid receptor mRNA and dysfunction of HPA axis in rats after removal of the cholinergic innervation to hippocampus.
    Han, JS
    Bizon, JL
    Chun, HJ
    Maus, CE
    Gallagher, M
    EUROPEAN JOURNAL OF NEUROSCIENCE, 2002, 16 (07) : 1399 - 1404
  • [35] ASSOCIATION OF GLUCOCORTICOID RECEPTOR BINDING PROTEIN FKBP5 WITH ALCOHOL DRINKING BEHAVIOR IN KNOCK OUT MICE AND HUMAN SUBJECTS
    Yong, W.
    Eng, M. Y.
    Shou, W.
    Wall, T. L.
    Liang, T.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2011, 35 (06) : 136A - 136A
  • [36] Anxiolytic impact of Apelin-13 in a rat model of Alzheimer's disease: Involvement of glucocorticoid receptor and FKBP5
    Aminyavari, Samaneh
    Zahmatkesh, Maryam
    Khodagholi, Fariba
    Sanati, Mehdi
    PEPTIDES, 2019, 118
  • [37] Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure
    Bortsov, Andrey V.
    Smith, Jennifer E.
    Diatchenko, Luda
    Soward, April C.
    Ulirsch, Jacob C.
    Rossi, Catherine
    Swor, Robert A.
    Hauda, William E.
    Peak, David A.
    Jones, Jeffrey S.
    Holbrook, Debra
    Rathlev, Niels K.
    Foley, Kelly A.
    Lee, David C.
    Collette, Renee
    Domeier, Robert M.
    Hendry, Phyllis L.
    McLean, Samuel A.
    PAIN, 2013, 154 (08) : 1419 - 1426
  • [38] The effect of antidepressant drugs on the HPA axis activity, glucocorticoid receptor and FK506 binding protein 51 (FKBP-51) concentration in animal model of depression
    Otczyk, M.
    Budziszewska, B.
    Jaworska-Feil, L.
    Basta-Kaim, A.
    Kubera, M.
    Regulska, M.
    Leskiewicz, M.
    Lason, W.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2008, 18 : S23 - S24
  • [39] Adolescent Stress Alters FKBP5-Glucocorticoid Receptor Interactions in the Adult Hippocampus of Female, but Not Male, Rats
    Rowson, Sydney
    Bekhbat, Mandakh
    Kelly, Sean
    Binder, Elisabeth
    Weinshenker, David
    Neigh, Gretchen
    NEUROPSYCHOPHARMACOLOGY, 2018, 43 : S398 - S398
  • [40] Evidence for mineralocorticoid receptor facilitation of glucocorticoid receptor-dependent regulation of hypothalamic-pituitary-adrenal axis activity
    Spencer, RL
    Kim, PJ
    Kalman, BA
    Cole, MA
    ENDOCRINOLOGY, 1998, 139 (06) : 2718 - 2726
12345