Human-machine interface (HMI), as a medium for human to interact with machine, has gained more and more attention. Here, a glove-based HMI was proposed, integrated with ultra-stretchable strain sensors (USSs) based on functional liquid metal (FLM) and three-axis force sensors (TFSs) based on PDMS/MWCNT, to record bending angles and contact force of fingers, separately. The TFS endowed manipulator the ability of force perception so that it could better mimic the operations of skilled-workman. The USS and TFS have the advantages of high sensitivity, good linearity and low hysteresis, which enable the HMI with the capability of teleoperation and three-axis force perception.