Efficient syntheses of biologically active peptides of aquatic origin involving unusual amino acids

被引：0

作者：

Shioiri, T

Hamada, Y

机构：

[1] Nagoya City Univ, Fac Pharmaceut Sci, Mizuho Ku, Nagoya, Aichi 4678603, Japan

[2] Chiba Univ, Fac Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

来源：

SYNLETT | 2001年 / 02期

关键词：

peptides; biological activity; aquatic natural products; unusual amino acids; diphenyl phosphorazidate; diethyl phosphorocyanidate;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Many peptides of aquatic origin involving unusual amino acids have interesting biological activities as well as unique structures. in addition, the scarce availability of these peptides has prompted synthetic chemists to explore their synthesis suitable for the production of sufficient quantities. The proposed structures will be firmly established by chemical synthesis. This review describes recent efforts on the synthesis of unusual amino acids and on the total synthesis of various peptides of aquatic origin.

引用

页码：184 / 201

页数：18

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