Regioselective synthesis of oxepin and oxocin annulated quinoline heterocycles by ring-closing metathesis

被引：7

作者：

Majumdar, Krishna C. ^{[1
]}

Debnath, Pradip ^{[1
]}

Taher, Abu ^{[1
]}

机构：

[1] Univ Kalyani, Dept Chem, Kalyani 741235, W Bengal, India

来源：

LETTERS IN ORGANIC CHEMISTRY | 2008年 / 5卷 / 03期

关键词：

ring-closing metathesis; oxepine; oxocine; quinoline derivatives; Grubb's catalyst;

D O I：

10.2174/157017808783955871

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Regioselective synthesis of oxepin and oxocin annulated quinoline heterocycles by the combination of Claisen rearrangement and ring-closing metathesis reaction is described. The ring-closing metathesis (RCM) and ring-closing enyne metathesis (RCEM) proceeded smoothly in the presence of Grubbs' catalyst A or B in toluene under nitrogen atmosphere without deactivation of the basic quinoline nitrogen.

引用

页码：169 / 173

页数：5

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