Inferring regulatory networks

被引：27

作者：

Li, Huai ^{[1
]}

Xuan, Jianhua ^{[2
]}

Wang, Yue ^{[2
]}

Zhan, Ming ^{[1
]}

机构：

[1] NIA, Bioinformat Unit, Branch Res Resources, NIH, Baltimore, MD 21224 USA

[2] Virginia Polytech Inst & State Univ, Dept Elect Comp & Biomed Engn, Arlington, VA USA

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2008年 / 13卷

关键词：

systems biology; regulatory network; coexpression; pathway dynamics; Modeling and inference; transcriptional intervention; review;

D O I：

10.2741/2677

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The discovery of regulatory networks is an important aspect in the post genomic research. The process requires integrated efforts of experimental and computational strategies by employing the systems biology approach. This review summarizes some of the major themes in computational inference of regulatory networks based on gene expression and other data sources, including transcriptional module identification, network topology inference, and network analysis. Popular solutions to each of these problems and their relative merits are discussed.

引用

页码：263 / 275

页数：13

共 50 条

[21] Inferring Parameters of Gene Regulatory Networks via Particle Filtering
Xiaohu Shen
Haris Vikalo
[J]. EURASIP Journal on Advances in Signal Processing, 2010
[22] Inferring Gene Regulatory Networks from a Population of Yeast Segregants
Chen Chen
Dabao Zhang
Tony R. Hazbun
Min Zhang
[J]. Scientific Reports, 9
[23] Inferring Gene Regulatory Networks by Context Dependent and Independent Effects
Gong, Wuming
Naoko, Koyano-Nakagawa
Garry, Daniel J.
[J]. JOURNAL OF MEDICAL DEVICES-TRANSACTIONS OF THE ASME, 2015, 9 (03):
[24] Inferring gene regulatory networks from genetical genomics data
Liu, Bing
Hoeschele, Ina
de la Fuente, Alberto
[J]. Handbook of Research on Computational Methodologies in Gene Regulatory Networks, 2009, : 79 - 107
[25] Inferring gene regulatory networks from multiple microarray datasets
Wang, Yong
Joshi, Trupti
Zhang, Xiang-Sun
Xu, Dong
Chen, Luonan
[J]. BIOINFORMATICS, 2006, 22 (19) : 2413 - 2420
[26] A Knowledge-Guided Approach for Inferring Gene Regulatory Networks
Hsiao, Yu-Ting
Lee, Wei-Po
[J]. INTELLIGENT COMPUTING IN BIOINFORMATICS, 2014, 8590 : 186 - 192
[27] A genetic algorithm for inferring time delays in gene regulatory networks
Wu, FY
Kusalik, AJ
Zhang, WJ
[J]. 2004 IEEE COMPUTATIONAL SYSTEMS BIOINFORMATICS CONFERENCE, PROCEEDINGS, 2004, : 610 - 611
[28] Inferring Gene Regulatory Networks from a Population of Yeast Segregants
Chen, Chen
Zhang, Dabao
Hazbun, Tony R.
Zhang, Min
[J]. SCIENTIFIC REPORTS, 2019, 9 (1)
[29] HiNO: An Approach for Inferring Hierarchical Organization from Regulatory Networks
Hartsperger, Mara L.
Strache, Robert
Stuempflen, Volker
[J]. PLOS ONE, 2010, 5 (11):
[30] NAIL, a software toolset for inferring, analyzing and visualizing regulatory networks
Hurley, Daniel G.
Cursons, Joseph
Wang, Yi Kan
Budden, David M.
Print, Cristin G.
Crampin, Edmund J.
[J]. BIOINFORMATICS, 2015, 31 (02) : 277 - 278

← 1 2 3 4 5 →