Activity-Based Profiling of 2-Oxoglutarate Oxygenases

被引：1
|
作者：
Geurink, Paul P. [3 ]
Florea, Bogdan I. [1 ,2 ]
Overkleeft, Herman S. [1 ,2 ]
机构：
[1] Leiden Univ, Leiden Inst Chem, NL-2300 RA Leiden, Netherlands
[2] Netherlands Prote Ctr, NL-2300 RA Leiden, Netherlands
[3] Netherlands Canc Inst, NL-1066 CX Amsterdam, Netherlands
来源：
CHEMISTRY & BIOLOGY | 2011年 / 18卷 / 05期
关键词：
FAMILIES;
D O I：
10.1016/j.chembiol.2011.05.002
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
2-Oxoglutarate oxygenases (2-OGs) are a large enzyme family involved in numerous processes in health and disease. Rotili et al. (2011) describe in this issue of Chemistry & Biology an activity-based protein profiling-based strategy with which the activity of individual members of the 2-OG family can be addressed in the context of complex biological systems.
引用
收藏
页码：557 / 559
页数：3
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