Brain metastasis of alveolar echinococcosis in a hyperendemic focus of Echinococcus multilocularis infection

An unusual female case, with alveolar echinococcosis (AE) disseminated from the primary hepatic Lesion to the brain by metastasis formation, was retrospectively identified during a community survey in Ningxia Hui Autonomous Region, northwest China in 2003. Among possible metastases of hepatic AE, locations to the brain are rare and usually fatal; and they have especially been assigned to concomitant immune suppression. An enhancing role of pregnancy, which may be suspected in this case, the favourable outcome after surgery and chemotherapy, and also a mental disability in a child following Long-term intrauterine exposure to mebendazole, make the report particularly unique. (c) 2005 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.