Homologous recombination: from model organisms to human disease

被引:0
|
作者
Modesti, Mauro [1 ]
Kanaar, Roland [1 ,2 ]
机构
[1] Erasmus Univ, Dept Cell Biol & Genet, NL-3000 DR Rotterdam, Netherlands
[2] Univ Hosp Rotterdam Daniel, Dept Radiat Oncol, NL-3008 AE Rotterdam, Netherlands
来源
GENOME BIOLOGY | 2001年 / 2卷 / 05期
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Recent experiments show that properly controlled recombination between homologous DNA molecules is essential for the maintenance of genome stability and for the prevention of tumorigenesis.
引用
收藏
页数:5
相关论文
共 50 条
  • [31] HOMOLOGOUS RECOMBINATION CATALYZED BY HUMAN CELL-EXTRACTS
    KUCHERLAPATI, RS
    SPENCER, J
    MOORE, PD
    MOLECULAR AND CELLULAR BIOLOGY, 1985, 5 (04) : 714 - 720
  • [32] PROSPECTS FOR HOMOLOGOUS RECOMBINATION IN HUMAN GENE-THERAPY
    VEGA, MA
    HUMAN GENETICS, 1991, 87 (03) : 245 - 253
  • [33] Homologous Recombination in Human Embryonic Stem Cells: A Tool for Advancing Cell Therapy and Understanding and Treating Human Disease
    Leavitt, Andrew D.
    Hamlett, Isla
    CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2011, 4 (04): : 298 - 305
  • [34] Modeling Disease in Human ESCs Using an Efficient BAC-Based Homologous Recombination System
    Song, Hoseok
    Chung, Sun-Ku
    Xu, Yang
    CELL STEM CELL, 2010, 6 (01) : 80 - 89
  • [35] A PARALLEL DNA TRIPLER AS A MODEL FOR THE INTERMEDIATE IN HOMOLOGOUS RECOMBINATION
    ZHURKIN, VB
    RAGHUNATHAN, G
    ULYANOV, NB
    CAMERINIOTERO, RD
    JERNIGAN, RL
    JOURNAL OF MOLECULAR BIOLOGY, 1994, 239 (02) : 181 - 200
  • [36] A transcriptomic model for homologous recombination deficiency in prostate cancer
    Adam B. Weiner
    Yang Liu
    Matthew McFarlane
    Pushpinder S. Bawa
    Eric V. Li
    Xin Zhao
    Ziwen Li
    Tanya Hammoud
    Munna Hazime
    R. Jeffrey Karnes
    Elai Davicioni
    Zachery R. Reichert
    Arul M. Chinnaiyan
    Tamara L. Lotan
    Daniel E. Spratt
    Edward M. Schaeffer
    Prostate Cancer and Prostatic Diseases, 2022, 25 : 659 - 665
  • [37] A transcriptomic model for homologous recombination deficiency in prostate cancer
    Weiner, Adam B.
    Liu, Yang
    McFarlane, Matthew
    Bawa, Pushpinder S.
    Li, Eric, V
    Zhao, Xin
    Li, Ziwen
    Hammoud, Tanya
    Hazime, Munna
    Karnes, R. Jeffrey
    Davicioni, Elai
    Reichert, Zachery R.
    Chinnaiyan, Arul M.
    Lotan, Tamara L.
    Spratt, Daniel E.
    Schaeffer, Edward M.
    PROSTATE CANCER AND PROSTATIC DISEASES, 2022, 25 (04) : 659 - 665
  • [38] INACTIVATION OF MOUSE ALPHA-GLOBIN GENES BY HOMOLOGOUS RECOMBINATION - MOUSE MODEL OF HBH DISEASE
    CHANG, JC
    LU, RH
    XU, SM
    MENESES, J
    CHAN, K
    PEDERSEN, R
    KAN, YW
    BLOOD, 1994, 84 (10) : A505 - A505
  • [39] Gene Correction by Homologous Recombination With Zinc Finger Nucleases in Primary Cells From a Mouse Model of a Generic Recessive Genetic Disease
    Connelly, Jon P.
    Barker, Jenny C.
    Pruett-Miller, Shondra
    Porteus, Matthew H.
    MOLECULAR THERAPY, 2010, 18 (06) : 1103 - 1110
  • [40] HOMOLOGOUS DISEASE A MODEL FOR AUTOIMMUNE DISEASE
    STASTNY, P
    STEMBRIDGE, VA
    VISCHER, TL
    ZIFF, M
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1965, 124 : 158 - +