Interleukin-22 acts as a mitochondrial protector

被引：7
|
作者：
Hwang, Seonghwan [1 ]
Feng, Dechun [1 ]
Gao, Bin [1 ]
机构：
[1] NIAAA, Lab Liver Dis, NIH, 5625 Fishers Lane, Bethesda, MD 20892 USA
来源：
THERANOSTICS | 2020年 / 10卷 / 17期
关键词：
Interleukin (IL)-22; mitochondrial protector; LIVER; IL-22; HEPATITIS; CELLS; REGENERATION; COLITIS; INNATE; INJURY; DRUG; MICE;
D O I：
10.7150/thno.48022
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Interleukin (IL) -22 has been increasingly recognized as a promising therapeutic option for various types of diseases. This commentary summarizes the novel mechanistic aspects of IL -22 for the treatment of liver diseases including the study by Chen et al. published in the recent issue of the Theranostics that elucidated the novel function of IL -22 as a mitochondrial protector for the adaptive defense against liver injury.
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页码：7836 / 7840
页数：5
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