Serological characteristics of HIV-1 isolates from an epidemic focus in the Gomel region in Republic of Belarus (1996)

被引：0
|
作者：
Shchelkanov, MY [1 ]
Yaroslavtseva, NG
Yudin, AN
Mirskov, YA
Yeremen, VF
Titov, LP
Rytik, OG
Karamov, EV
机构：
[1] DI Ivanovskii Inst Virol, Moscow 123098, Russia
[2] Belorussian Minist Publ Hlth, Inst Epidemiol & Microbiol, Minsk, BELARUS
来源：
VOPROSY VIRUSOLOGII | 1998年 / 43卷 / 05期
关键词：
human immunodeficiency virus; subtype; serotype; gp; 120; V3; loop; synthetic peptides; enzyme immunoassay;
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Immunoreactivity of sera obtained in 1996 from HIV-1-infected intravenous narcomaniacs from an epidemic focus in Gomel region, Belarus, is studied with a panel of 10-16-component synthetic peptides simulating apical epitope of surface glycoprotein gp120 V3 loop of HIV-1 variants. Comparative analysis of resultant spectra with representative immunoreactivity spectra of sera from a sampling of HIV-l-positive sera collected in 1986-1997 in different regions of the former USSR demonstrated a high homogeneity of immunoreactivity spectra of sera from Gomel region. Serotypes of HIV-1 AIC variants circulating in populations of intravenous narcomaniacs in the focus in Gomel region in 1996 and in Southern and South-Eastern Ukraine in 1995-1996 are similar. This confirms a previous conclusion about the prevalence of AIC serotype among intravenous narcomaniacs in the former USSR.
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页码：220 / 229
页数：10
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