Studying the Sensitivity of Graphene for Biosensor Applications

被引：0

作者：

Usikov, A. S. ^{[1
,2
]}

Lebedev, S. P. ^{[3
]}

Roenkov, A. D. ^{[4
]}

Barash, I. S. ^{[3
,4
]}

Novikov, S., V ^{[5
]}

Puzyk, M., V ^{[6
]}

Zubov, A., V ^{[2
]}

Makarov, Yu N. ^{[1
]}

Lebedev, A. A. ^{[3
]}

机构：

[1] Nitride Crystals Inc, Richmond, VA 23238 USA

[2] St Petersburg Natl Res Univ Informat Technol Mech, St Petersburg 197101, Russia

[3] Russian Acad Sci, Ioffe Phys Tech Inst, St Petersburg 194021, Russia

[4] Nitride Crystals Grp, St Petersburg 194156, Russia

[5] Aalto Univ, Espoo, Finland

[6] Herzen State Pedag Univ, St Petersburg 191186, Russia

来源：

TECHNICAL PHYSICS LETTERS | 2020年 / 46卷 / 05期

关键词：

graphene; silicon carbide; biosensor; fluorescein;

D O I：

10.1134/S1063785020050296

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We have studied the response of graphene-film-based chips on SiC substrates (the relative change in the chip resistance) to coming into contact with fluorescein (C20H12O5) in a wide range of its concentrations in a phosphate-buffered saline solution: from 1 x 10(-3)to 1 x 10(4)ng/mL (seven orders of magnitude). Fluorescein detection seems to be a simple and cheap model experiment to study the sensory ability of graphene in the way of biochips manufacturing. It has been shown that chips with wide terraces on a surface with a step width of about 1000 nm and heights of up to 5 nm made it possible to construct the calibration dependences of chip response on fluorescein concentration.

引用

页码：462 / 465

页数：4

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